HitPredict

Interactor 1: MOB1B (Q7L9L4)
MOB kinase activator 1B (Mob1 homolog 1A) (Mob1A) (Mob1B) (Mps one binder kinase activator-like 1A)
Gene: MOB1B

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.755

Property	Details
Experiments	32707033, 36736316, 19919647, 28514442, 33961781, 37536630, 19739119, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0035329 - hippo signaling GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 1088
+	Hs
		1333705 MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1198336 MOB3B_HUMAN (5-212): 3.49e-108: 311: 53.59		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1285989 MOB3A_HUMAN (5-212): 3.88e-106: 306: 53.11		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1174306 MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325787 MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325891 MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325791 MOB3B_HUMAN (5-212): 3.49e-108: 311: 53.59		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325844 MOB3A_HUMAN (5-212): 3.88e-106: 306: 53.11		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325785 MOB3C_HUMAN (5-212): 1.7e-105: 304: 48.80		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1185506 MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		1333714 MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		1069623 MOB1B_HUMAN (1-216): 4.62e-119: 338: 100.00		STK38_HUMAN (583-1065): 5.24e-146: 447: 40.58
+	Hs
		1069652 MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83		STK38_HUMAN (583-1065): 5.24e-146: 447: 40.58
+	Dm
		1099222 MOB1_DROME (1-216): 7.76e-116: 330: 87.96		Q24590_DROME (167-1039): 3.13e-139: 449: 39.64
+	Dm
		1278870 MOB1_DROME (1-216): 7.76e-116: 330: 87.96		WARTS_DROME (167-1039): 7.21e-137: 443: 39.71
+	Dm
		1278869 MOB1_DROME (1-216): 7.76e-116: 330: 87.96		TRC_DROME (577-1049): 1.4e-142: 438: 39.66
+	Hs
		117030 MOB1A_HUMAN (1-216): 5.45e-119: 338: 95.83		SGK1_HUMAN (608-1042): 1.07e-131: 408: 28.51
+	Sp
		293187 MOB1_SCHPO (3-211): 1.87e-100: 291: 55.50		SID2_SCHPO (501-1052): 1.07e-137: 430: 27.87
+	Ca
		1124241 MOB2_CANAL (25-216): 4.12e-88: 263: 41.15		CBK1_CANAL (414-1051): 8.52e-146: 456: 32.82
+	Sp
		140739 MOB2_SCHPO (14-215): 2.45e-87: 259: 39.60		ORB6_SCHPO (585-1049): 2.35e-146: 448: 40.22