HitPredict

Interactor 1: EYA2 (O00167)
Eyes absent homolog 2 (EC 3.1.3.48)
Gene: EYA2

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27880917
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030154 - cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 538 Hs			1 2229
+	Hs
		318639 EYA4_HUMAN (1-538): 2.16e-177: 515: 56.22		PRC2B_HUMAN (1-2229): 0: 619: 100.00
+	Hs
		118625 EYA2_HUMAN (1-538): 0: 616: 100.00		NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59
+	Hs
		118599 EYA2_HUMAN (1-538): 0: 616: 100.00		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		318762 EYA4_HUMAN (1-538): 2.16e-177: 515: 56.22		NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59
+	Hs
		318703 EYA4_HUMAN (1-538): 2.16e-177: 515: 56.22		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		123982 SPT5H_HUMAN (5-305): 2.65e-35: 143: 15.22		NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37
+	Dm
		90744 E1JI93_DROME (6-263): 1.81e-26: 116: 13.33		M9MSL0_DROME (2-1780): 2.17e-40: 167: 6.96
+	Hs
		967233 EWS_HUMAN (19-268): 1.95e-20: 96.9: 16.91		NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37
+	Hs
		124057 SPT5H_HUMAN (5-305): 2.65e-35: 143: 15.22		MINT_HUMAN (296-2220): 2.45e-17: 91.8: 8.49
+	Hs
		124137 SPT5H_HUMAN (5-305): 2.65e-35: 143: 15.22		NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59
+	Hs
		124053 SPT5H_HUMAN (5-305): 2.65e-35: 143: 15.22		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		967303 EWS_HUMAN (19-268): 1.95e-20: 96.9: 16.91		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		967374 EWS_HUMAN (19-268): 1.95e-20: 96.9: 16.91		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		967173 EWS_HUMAN (19-268): 1.95e-20: 96.9: 16.91		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		967541 EWS_HUMAN (19-268): 1.95e-20: 96.9: 16.91		PCLO_HUMAN (15-1836): 2.75e-12: 75.1: 7.64
+	Hs
		820892 EWS_HUMAN (19-268): 1.95e-20: 96.9: 16.91		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Dm
		52421 A1Z7J7_DROME (20-261): 1.58e-21: 101: 14.52		X2JDJ3_DROME (949-2220): 1.7e-09: 65.6: 9.45
+	Hs
		867119 SC24C_HUMAN (4-259): 2.46e-12: 71.9: 14.23		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Mm
		1351630 PCLO_MOUSE (76-268): 1.08e-09: 63.8: 7.73		PCLO_MOUSE (15-1858): 1.65e-14: 82.4: 8.18
+	Dm
		113976 M9PB30_DROME (78-260): 3.05e-10: 65.3: 12.31		M9PB30_DROME (1183-1955): 1.05e-13: 79.8: 9.22