HitPredict

Interactor 1: Q7SZP8 (Q7SZP8)
Protein Tob1 (Transducer of ERBB2, 1b)
Gene: tob1b

Interactor 2: Q8AY16 (Q8AY16)
Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member)
Gene: smad3b

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16890162
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 322 Dr			1 423
+	Dr
		1186359 Q7SZP8_DANRE (1-322): 4.27e-168: 471: 100.00		Q8AY15_DANRE (1-423): 0: 632: 94.12
+	Dr
		1186363 Q7SZR1_DANRE (1-322): 5.11e-140: 400: 83.79		Q8AY16_DANRE (1-423): 0: 638: 100.00
+	Dr
		1186362 Q7SZR1_DANRE (1-322): 5.11e-140: 400: 83.79		Q8AY15_DANRE (1-423): 0: 632: 94.12
+	Hs
		841379 TOB1_HUMAN (1-322): 5.66e-142: 406: 74.57		SMAD3_HUMAN (2-423): 0: 621: 93.16
+	Hs
		171372 TOB1_HUMAN (1-322): 5.66e-142: 406: 74.57		SMAD9_HUMAN (2-423): 0: 573: 58.23
+	Hs
		841388 TOB1_HUMAN (1-322): 5.66e-142: 406: 74.57		SMAD1_HUMAN (2-423): 0: 567: 59.05
+	Hs
		841398 TOB1_HUMAN (1-322): 5.66e-142: 406: 74.57		SMAD5_HUMAN (2-423): 0: 565: 58.53
+	Dm
		60229 A4V4L0_DROME (1-292): 2.2e-90: 281: 40.41		MAD_DROME (2-423): 0: 590: 60.00
+	Hs
		841384 TOB1_HUMAN (1-322): 5.66e-142: 406: 74.57		SMAD4_HUMAN (22-413): 5.92e-138: 407: 34.88
+	Mm
		978996 BTG2_MOUSE (1-116): 1.63e-54: 176: 39.83		SMAD9_MOUSE (2-423): 0: 575: 61.89
+	Mm
		936604 BTG2_MOUSE (1-116): 1.63e-54: 176: 39.83		SMAD1_MOUSE (2-423): 0: 568: 59.05