HitPredict

Interactor 1: Q7SZR1 (Q7SZR1)
Protein Tob1 (Transducer of ERBB2, 1a)
Gene: tob1a

Interactor 2: Q8AY15 (Q8AY15)
Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member)
Gene: smad3a

Species: Danio rerio

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16890162
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 322 Dr			1 425
+	Dr
		1186359 Q7SZP8_DANRE (1-322): 1.89e-161: 454: 82.88		Q8AY15_DANRE (1-425): 0: 651: 100.00
+	Dr
		1186360 Q7SZP8_DANRE (1-322): 1.89e-161: 454: 82.88		Q8AY16_DANRE (1-425): 0: 637: 94.12
+	Dr
		1186363 Q7SZR1_DANRE (1-322): 5.55e-159: 448: 100.00		Q8AY16_DANRE (1-425): 0: 637: 94.12
+	Hs
		841379 TOB1_HUMAN (1-322): 3.76e-154: 437: 77.59		SMAD3_HUMAN (2-425): 0: 641: 97.17
+	Hs
		171372 TOB1_HUMAN (1-322): 3.76e-154: 437: 77.59		SMAD9_HUMAN (2-425): 0: 585: 58.87
+	Hs
		841398 TOB1_HUMAN (1-322): 3.76e-154: 437: 77.59		SMAD5_HUMAN (2-425): 0: 583: 59.40
+	Hs
		841388 TOB1_HUMAN (1-322): 3.76e-154: 437: 77.59		SMAD1_HUMAN (2-425): 0: 582: 60.78
+	Dm
		60229 A4V4L0_DROME (1-246): 3.34e-80: 255: 45.78		MAD_DROME (2-425): 0: 602: 60.91
+	Hs
		841384 TOB1_HUMAN (1-322): 3.76e-154: 437: 77.59		SMAD4_HUMAN (22-414): 6.24e-143: 420: 34.56
+	Mm
		978996 BTG2_MOUSE (1-115): 3.1e-53: 173: 40.17		SMAD9_MOUSE (2-425): 0: 585: 62.82
+	Mm
		936604 BTG2_MOUSE (1-115): 3.1e-53: 173: 40.17		SMAD1_MOUSE (2-425): 0: 582: 60.56