Protein: ZNF74
Zinc finger protein 74 (Zinc finger protein 520) (hZNF7)

Gene: ZNF74
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q16587

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1099947

TIF1B
Transcription intermediary factor 1-beta

6

20

Small-scale

0.726

High

1128629

ZN460
Zinc finger protein 460

1

17

High-throughput

0.691

High

1159272

IKZF4
Zinc finger protein Eos

1

18

High-throughput

0.691

High

1159276

RBAK
RB-associated KRAB zinc finger protein

1

2

High-throughput

0.691

High

613057

EGR1
Early growth response protein 1

1

16

High-throughput

0.618

High

189172

IPO8
Importin-8

2

18

High-throughput

0.601

High

571993

TRI27
Zinc finger protein RFP

2

16

High-throughput

0.601

High

1159263

P3H2
Prolyl 3-hydroxylase 2

2

0

High-throughput

0.576

High

65266

ZN316
Zinc finger protein 316

1

5

High-throughput

0.575

High

600309

ZNF24
Zinc finger protein 24

1

18

High-throughput

0.575

High

625414

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.575

High

1157734

DDB1
DNA damage-binding protein 1

1

3

High-throughput

0.575

High

1159275

ZN304
Zinc finger protein 304

1

9

High-throughput

0.575

High

1159269

VWCE
von Willebrand factor C and EGF domain-containing protein

2

20

High-throughput

0.574

High

1132085

LTBP2
Latent-transforming growth factor beta-binding protein 2

2

20

High-throughput

0.549

High

1159266

LTBP4
Latent-transforming growth factor beta-binding protein 4

2

20

High-throughput

0.549

High

667319

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

Small-scale

0.537

High

156275

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

4

High-throughput

0.536

High

159355

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

6

High-throughput

0.536

High

323392

TRI37
E3 ubiquitin-protein ligase TRIM37

1

9

High-throughput

0.536

High

857467

NOTC1
Neurogenic locus notch homolog protein 1

1

20

High-throughput

0.536

High

1159259

RN187
E3 ubiquitin-protein ligase RNF187

1

9

High-throughput

0.536

High

1159261

FBX11
F-box only protein 11

1

1

High-throughput

0.536

High

1159267

TRI41
E3 ubiquitin-protein ligase TRIM41

1

16

High-throughput

0.536

High

1159273

SAV1
Protein salvador homolog 1

1

2

High-throughput

0.536

High

1159279

NOTC3
Neurogenic locus notch homolog protein 3

1

19

High-throughput

0.536

High

1159258

TCAL5
Transcription elongation factor A protein-like 5

1

0

High-throughput

0.513

High

270555

LRP4
Low-density lipoprotein receptor-related protein 4

1

9

High-throughput

0.489

High

1159268

SORL
Sortilin-related receptor

1

9

High-throughput

0.489

High

1159271

LZTS2
Leucine zipper putative tumor suppressor 2

1

3

High-throughput

0.489

High

1159277

FBLN5
Fibulin-5

1

20

High-throughput

0.489

High

1159281

JAG2
Protein jagged-2

1

15

High-throughput

0.489

High

461530

HS90A
Heat shock protein HSP 90-alpha

1

4

High-throughput

0.479

High

468421

HS90B
Heat shock protein HSP 90-beta

1

4

High-throughput

0.479

High

934677

TERA
Transitional endoplasmic reticulum ATPase

1

1

Small-scale

0.479

High

180832

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.445

High

325858

UBR5
E3 ubiquitin-protein ligase UBR5

1

5

High-throughput

0.445

High

731341

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.445

High

1097312

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.445

High

1122242

SCRIB
Protein scribble homolog

1

2

High-throughput

0.445

High

1159257

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

12

High-throughput

0.445

High

1159260

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

4

High-throughput

0.445

High

1159274

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

2

High-throughput

0.445

High

1159280

CHIP
E3 ubiquitin-protein ligase CHIP

1

2

High-throughput

0.445

High

1159282

DCAF1
DDB1- and CUL4-associated factor 1

1

1

High-throughput

0.445

High

1159265

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

1159278

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.426

High

347055

BAG2
BAG family molecular chaperone regulator 2

1

5

High-throughput

0.407

High

673771

LAMA1
Laminin subunit alpha-1

1

2

High-throughput

0.407

High

772314

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

20

High-throughput

0.407

High

1159262

FRAS1
Extracellular matrix organizing protein FRAS1

1

16

High-throughput

0.407

High

1159264

DJC10
DnaJ homolog subfamily C member 10

1

11

High-throughput

0.407

High

387117

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.279

Low

1144597

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

0

High-throughput

0.279

Low

1159256

KIF7
Kinesin-like protein KIF7

1

0

High-throughput

0.279

Low

1159270

SNX18
Sorting nexin-18

1

0

High-throughput

0.279

Low

133359

DCTN6
Dynactin subunit 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025