HitPredict

Interactor 1: GTPB1 (O00178)
GTP-binding protein 1 (G-protein 1) (GP-1) (GP1)
Gene: GTPBP1

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 465
+	Hs
		228570 GTPB2_HUMAN (43-582): 9.5e-147: 441: 48.47		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228009 ERF3B_HUMAN (9-575): 2.44e-142: 430: 19.14		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227130 EF1A1_HUMAN (155-594): 1.65e-133: 402: 19.62		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227242 EF1A2_HUMAN (155-595): 4.64e-131: 396: 19.38		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226427 ERF3A_HUMAN (80-575): 7.53e-129: 391: 20.76		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1219365 GTPB2_HUMAN (43-582): 9.5e-147: 441: 48.47		CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58
+	Hs
		312566 EF1A1_HUMAN (155-594): 1.65e-133: 402: 19.62		ARI2_HUMAN (222-464): 1.56e-64: 217: 20.82
+	Sc
		367642 EF1A_YEAST (155-576): 1.54e-126: 384: 21.57		UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72
+	Xl
		568008 EF1A2_XENLA (155-593): 6.41e-131: 395: 20.08		Q7SY79_XENLA (1-149): 2.25e-49: 179: 19.33
+	Zm
		24695 A0A1D6M1G2_MAIZE (155-573): 3.65e-141: 421: 19.26		A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70
+	Hs
		475654 EF1A2_HUMAN (155-595): 4.64e-131: 396: 19.38		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		1012702 EF1A3_ARATH (155-593): 4.51e-127: 385: 19.19		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		570784 EFTU_ARATH (114-575): 6.1e-125: 380: 19.46		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	Zm
		24723 B6UHJ4_MAIZE (155-580): 4.87e-126: 382: 19.74		A0A1D6IJX7_MAIZE (233-459): 1.19e-26: 116: 21.70
+	Hs
		226841 EFTU_HUMAN (161-577): 2.79e-16: 84: 25.64		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		229149 HBS1L_HUMAN (149-524): 6.33e-13: 73.9: 25.51		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1377778 HBS1L_HUMAN (149-524): 6.33e-13: 73.9: 25.51		ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67
+	Hs
		475481 EFTU_HUMAN (161-577): 2.79e-16: 84: 25.64		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		476620 HBS1L_HUMAN (149-524): 6.33e-13: 73.9: 25.51		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47