HitPredict

Interactor 1: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Interactor 2: TRI42 (Q8IWZ5)
Tripartite motif-containing protein 42
Gene: TRIM42

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.80	0.731

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	EGF_CA~fn3
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 723
+	Hs
		484656 NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95		TRI42_HUMAN (1-723): 0: 600: 100.00
+	Hs
		254223 SLIT1_HUMAN (68-230): 2.49e-09: 58.9: 17.96		TRI42_HUMAN (1-723): 0: 600: 100.00
+	Hs
		536897 NT2NA_HUMAN (1-236): 1e-44: 151: 100.00		TRI27_HUMAN (222-657): 2.77e-70: 240: 10.62
+	Hs
		734593 CRUM1_HUMAN (8-143): 8.13e-24: 101: 28.31		TRI23_HUMAN (119-477): 2.49e-63: 223: 17.09
+	Dm
		706673 FAT_DROME (145-236): 1.12e-20: 92.4: 24.17		Q9W378_DROME (146-497): 5.56e-61: 224: 16.71
+	Hs
		262156 NOTC1_HUMAN (67-233): 4.88e-17: 81.9: 29.94		TRIM3_HUMAN (126-698): 1.77e-65: 232: 12.63
+	Hs
		804274 NOTC1_HUMAN (67-233): 4.88e-17: 81.9: 29.94		TRI67_HUMAN (186-526): 9.04e-65: 231: 16.88
+	Hs
		804231 NOTC1_HUMAN (67-233): 4.88e-17: 81.9: 29.94		TIF1B_HUMAN (138-485): 8.05e-64: 229: 16.30
+	Hs
		1172068 TEN3_HUMAN (148-233): 1.23e-12: 68.9: 19.30		TRI67_HUMAN (186-526): 9.04e-65: 231: 16.88
+	Hs
		254222 SLIT1_HUMAN (68-230): 2.49e-09: 58.9: 17.96		TRI67_HUMAN (186-526): 9.04e-65: 231: 16.88
+	Hs
		164378 FAT1_HUMAN (138-236): 1.66e-24: 103: 28.43		TRI66_HUMAN (132-466): 3.08e-36: 149: 16.44
+	Hs
		164370 NOTC2_HUMAN (8-180): 9.42e-16: 78.1: 27.84		TRI66_HUMAN (132-466): 3.08e-36: 149: 16.44