HitPredict

Interactor 1: RPH1 (P39956)
DNA damage-responsive transcriptional repressor RPH1
Gene: RPH1

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	17525156, 21067515
Identification Methods	enzymatic study, unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 796 Sc			1 136
+	Hs
		301134 KDM4B_HUMAN (14-616): 4.8e-123: 398: 28.15		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		301136 KDM4B_HUMAN (14-616): 4.8e-123: 398: 28.15		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		935232 KDM4C_HUMAN (14-627): 3.09e-121: 392: 25.67		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952622 KDM4C_HUMAN (14-627): 3.09e-121: 392: 25.67		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		1174653 KDM4C_HUMAN (14-627): 3.09e-121: 392: 25.67		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	Hs
		301146 KDM4B_HUMAN (14-616): 4.8e-123: 398: 28.15		H3C_HUMAN (1-136): 8.2e-59: 179: 86.03
+	Dm
		356098 KDM4B_DROME (10-402): 7.28e-124: 385: 34.25		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Hs
		935163 ZN184_HUMAN (302-762): 1.89e-120: 382: 12.21		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952581 ZN184_HUMAN (302-762): 1.89e-120: 382: 12.21		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		256961 KDM4A_HUMAN (4-501): 7.72e-117: 380: 28.85		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		256963 KDM4A_HUMAN (4-501): 7.72e-117: 380: 28.85		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		256973 KDM4A_HUMAN (4-501): 7.72e-117: 380: 28.85		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Dm
		356095 KDM4A_DROME (11-477): 2.57e-118: 368: 29.14		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Hs
		935310 ZN226_HUMAN (267-643): 3.6e-52: 196: 7.08		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952664 ZN226_HUMAN (267-643): 3.6e-52: 196: 7.08		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		952558 ZN570_HUMAN (320-542): 8.75e-28: 120: 8.12		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Sc
		902038 GIS1_YEAST (524-763): 1.82e-29: 127: 40.15		H3_YEAST (1-136): 1.51e-56: 174: 100.00
+	Hs
		666522 KDM5A_HUMAN (12-188): 2.09e-20: 99.1: 16.33		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		666523 KDM5A_HUMAN (12-188): 2.09e-20: 99.1: 16.33		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		666535 KDM5A_HUMAN (12-188): 2.09e-20: 99.1: 16.33		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03