HitPredict

Interactor 1: BRAP (Q7Z569)
BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63)
Gene: BRAP

Interactor 2: BRAP (Q7Z569)
BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63)
Gene: BRAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 25820252, 23554956, 14724641
Identification Methods two hybrid, affinity chromatography technology, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_2~zf-RING_2, zf-UBP~zf-UBP
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0000165 - MAPK cascade
GO:0003676 - nucleic acid binding
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
and 9 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 592
Hs

1 592
+ Dm
+ Hs
+ At
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024