HitPredict

Interactor 1: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Interactor 2: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26841866
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ENT~ENT
Common GO terms	GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006325 - chromatin organization GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1322 Hs			1 1322
+	Hs
		1056880 EMSY_HUMAN (1-1322): 5.68e-132: 441: 100.00		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		1056827 MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Dm
		113976 M9PB30_DROME (664-1317): 8.4e-18: 92.6: 9.55		M9PB30_DROME (664-1317): 8.4e-18: 92.6: 9.55
+	Dm
		1182373 Q9VLS7_DROME (186-1322): 1.42e-23: 111: 9.73		Q7KU92_DROME (113-1127): 4.86e-11: 70.2: 14.96
+	Hs
		1303336 MUC4_HUMAN (75-477): 6.47e-14: 79.4: 11.34		MUC4_HUMAN (75-477): 6.47e-14: 79.4: 11.34
+	Hs
		1264771 TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		152667 KMT2C_HUMAN (136-1005): 1.04e-12: 75.6: 6.91		KMT2D_HUMAN (261-1253): 1.13e-12: 75.2: 7.65
+	Mm
		1351630 PCLO_MOUSE (784-1313): 3.46e-11: 70.6: 8.46		PCLO_MOUSE (784-1313): 3.46e-11: 70.6: 8.46
+	Hs
		1192113 HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Sp
		1013617 PAN1_SCHPO (74-1314): 2.45e-10: 67.5: 7.95		PAN1_SCHPO (74-1314): 2.45e-10: 67.5: 7.95
+	Sc
		697601 FLO1_YEAST (325-1311): 2.98e-09: 64: 10.98		FLO1_YEAST (325-1311): 2.98e-09: 64: 10.98
+	Hs
		1336185 MAGE1_HUMAN (599-1076): 3.61e-09: 63.6: 11.34		MAGE1_HUMAN (599-1076): 3.61e-09: 63.6: 11.34