HitPredict

Interactor 1: TAFA3 (Q7Z5A8)
Chemokine-like protein TAFA-3
Gene: TAFA3

Interactor 2: SORL (Q92673)
Sortilin-related receptor (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (SorLA)
Gene: SORL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 2214
+	Hs
		1232364 TAFA2_HUMAN (1-132): 6.63e-66: 197: 62.88		SORL_HUMAN (1-2214): 0: 1927: 100.00
+	Hs
		1269012 TAFA4_HUMAN (14-133): 5.5e-52: 162: 66.67		SORL_HUMAN (1-2214): 0: 1927: 100.00
+	Hs
		351081 TAFA3_HUMAN (1-133): 1.43e-67: 201: 100.00		LDLR_HUMAN (1077-1278): 2.77e-29: 129: 34.48
+	Hs
		351086 TAFA2_HUMAN (1-132): 6.63e-66: 197: 62.88		LDLR_HUMAN (1077-1278): 2.77e-29: 129: 34.48
+	Hs
		957620 TAFA3_HUMAN (1-133): 1.43e-67: 201: 100.00		LRP2_HUMAN (1316-1712): 1.36e-18: 95.8: 17.49
+	Hs
		1190932 TAFA3_HUMAN (1-133): 1.43e-67: 201: 100.00		LRP1B_HUMAN (1311-1577): 6.86e-10: 66.9: 10.37
+	Hs
		270312 TAFA2_HUMAN (1-132): 6.63e-66: 197: 62.88		LRP6_HUMAN (1445-1549): 6.8e-11: 70.1: 36.94
+	Hs
		957632 TAFA4_HUMAN (14-133): 5.5e-52: 162: 66.67		LRP2_HUMAN (1316-1712): 1.36e-18: 95.8: 17.49