Protein: CDKL2
Cyclin-dependent kinase-like 2 (EC 2.7.11.22) (Protein kinase p56 KKIAMRE) (Serine/threonine-protein kinase KKIAMRE)

Gene: CDKL2
Organism: Homo sapiens
Interactions: 70
UniProt ID: Q92772

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

461777

HS90A
Heat shock protein HSP 90-alpha

2

20

High-throughput

0.789

High

1202061

HS905
Putative heat shock protein HSP 90-alpha A5

2

20

High-throughput

0.754

High

1202109

HS904
Putative heat shock protein HSP 90-alpha A4

2

20

High-throughput

0.712

High

322113

CDK14
Cyclin-dependent kinase 14

1

18

High-throughput

0.691

High

854200

KI67
Proliferation marker protein Ki-67

1

5

High-throughput

0.691

High

1087678

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

11

High-throughput

0.691

High

1106021

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

13

High-throughput

0.691

High

1130801

RRP5
Protein RRP5 homolog

1

2

High-throughput

0.691

High

1140643

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.691

High

1368233

RBM14
RNA-binding protein 14

1

5

High-throughput

0.691

High

1368242

RBM28
RNA-binding protein 28

1

5

High-throughput

0.618

High

1158456

CDC37
Hsp90 co-chaperone Cdc37

1

8

High-throughput

0.618

High

123791

MYO1C
Unconventional myosin-Ic

1

14

High-throughput

0.536

High

123922

MYO1F
Unconventional myosin-If

1

16

High-throughput

0.536

High

227937

MYO1B
Unconventional myosin-Ib

1

11

High-throughput

0.536

High

257919

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.536

High

277761

H2AY
Core histone macro-H2A.1

1

6

High-throughput

0.536

High

414331

P53
Cellular tumor antigen p53

1

6

High-throughput

0.536

High

451230

NFL
Neurofilament light polypeptide

1

5

High-throughput

0.536

High

587757

DESP
Desmoplakin

1

19

High-throughput

0.536

High

608681

DDX5
Probable ATP-dependent RNA helicase DDX5

1

3

High-throughput

0.536

High

669961

MCM3
DNA replication licensing factor MCM3

1

12

High-throughput

0.536

High

774099

ADDA
Alpha-adducin

1

2

High-throughput

0.536

High

937312

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

6

High-throughput

0.536

High

983546

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

7

High-throughput

0.536

High

984225

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

High-throughput

0.536

High

1028836

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

8

High-throughput

0.536

High

1035819

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.536

High

1058901

ZO1
Tight junction protein 1

1

6

High-throughput

0.536

High

1120788

DSG2
Desmoglein-2

1

6

High-throughput

0.536

High

1126493

CAPR1
Caprin-1

1

5

High-throughput

0.536

High

1130368

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.536

High

1143453

PCM1
Pericentriolar material 1 protein

1

2

High-throughput

0.536

High

1160712

DREB
Drebrin

1

6

High-throughput

0.536

High

1215545

FRY
Protein furry homolog

1

1

High-throughput

0.536

High

1271473

DHX30
ATP-dependent RNA helicase DHX30

1

5

High-throughput

0.536

High

1336263

LS14A
Protein LSM14 homolog A

1

2

High-throughput

0.536

High

1350996

DDX54
ATP-dependent RNA helicase DDX54

1

9

High-throughput

0.536

High

1368234

NEB2
Neurabin-2

1

10

High-throughput

0.536

High

1368235

PKP2
Plakophilin-2

1

12

High-throughput

0.536

High

1368238

DDX47
Probable ATP-dependent RNA helicase DDX47

1

9

High-throughput

0.536

High

1368239

PININ
Pinin

1

1

High-throughput

0.536

High

1368241

DDX18
ATP-dependent RNA helicase DDX18

1

8

High-throughput

0.536

High

1368243

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.536

High

1368244

BCLF1
Bcl-2-associated transcription factor 1

1

4

High-throughput

0.536

High

1368248

MRT4
mRNA turnover protein 4 homolog

1

3

High-throughput

0.536

High

1368249

DDX52
Probable ATP-dependent RNA helicase DDX52

1

5

High-throughput

0.536

High

1368250

TR150
Thyroid hormone receptor-associated protein 3

1

7

High-throughput

0.536

High

1368252

UTP18
U3 small nucleolar RNA-associated protein 18 homolog

1

8

High-throughput

0.536

High

1043717

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.513

High

1139983

RRS1
Ribosome biogenesis regulatory protein homolog

1

0

High-throughput

0.513

High

1281511

CENPV
Centromere protein V

1

0

High-throughput

0.513

High

1368237

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.513

High

1368240

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.513

High

1368246

GBG12

1

0

High-throughput

0.513

High

1368251

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.513

High

422766

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

866775

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.489

High

915151

CAZA1
F-actin-capping protein subunit alpha-1

1

1

High-throughput

0.489

High

1143216

PLEC
Plectin

1

11

High-throughput

0.489

High

1157240

AINX
Alpha-internexin

1

6

High-throughput

0.489

High

1332199

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.489

High

1368245

CING
Cingulin

1

11

High-throughput

0.489

High

1368247

LIMA1
LIM domain and actin-binding protein 1

1

3

High-throughput

0.489

High

989768

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

1

High-throughput

0.479

High

1220706

RN123
E3 ubiquitin-protein ligase RNF123

1

5

High-throughput

0.479

High

1207504

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

1

High-throughput

0.445

High

884182

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

1368236

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1307051

KR111
Keratin-associated protein 11-1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025