HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010629 - negative regulation of gene expression
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 1241
+	Hs
		619245 LEG9C_HUMAN (1-355): 6.62e-140: 402: 94.10		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		619239 LEG9B_HUMAN (1-355): 4.01e-139: 400: 94.94		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		121109 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		1086535 LEG9B_HUMAN (1-355): 4.01e-139: 400: 94.94		AT2B3_HUMAN (1-1241): 0: 1164: 71.63
+	Hs
		119157 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		588620 LEG9C_HUMAN (1-355): 6.62e-140: 402: 94.10		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		121164 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		AT2B3_HUMAN (1-1241): 0: 1164: 71.63
+	Hs
		121142 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		AT2B2_HUMAN (3-1241): 0: 1154: 68.59
+	Hs
		572285 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		119077 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		393024 LEG3_HUMAN (5-147): 5.77e-41: 145: 37.33		AT1A1_HUMAN (34-1053): 0: 737: 23.37