HitPredict

Interactor 1: NECA2 (Q7Z6G3)
N-terminal EF-hand calcium-binding protein 2 (EF-hand calcium-binding protein 2) (Neuronal calcium-binding protein 2) (Synaptotagmin-interacting protein 2) (Stip-2)
Gene: NECAB2

Interactor 2: LNX1 (Q8TBB1)
E3 ubiquitin-protein ligase LNX (EC 2.3.2.27) (Ligand of Numb-protein X 1) (Numb-binding protein 1) (PDZ domain-containing RING finger protein 2) (RING-type E3 ubiquitin transferase LNX)
Gene: LNX1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

Property	Details
Experiments	25416956, 16189514, 21516116, 32296183, 29892012, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 386 Hs			1 728
+	Hs
		1238226 NECA1_HUMAN (61-380): 2.51e-175: 493: 47.35		LNX1_HUMAN (1-728): 1.08e-139: 429: 100.00
+	Hs
		1191765 NECA2_HUMAN (1-386): 0: 666: 100.00		INADL_HUMAN (261-396): 1.13e-15: 83.6: 21.74
+	Hs
		61102 NECA2_HUMAN (1-386): 0: 666: 100.00		A5PKX9_HUMAN (66-363): 2.47e-15: 82.4: 11.71