HitPredict

Interactor 1: LEG9 (O00182)
Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21)
Gene: LGALS9

Interactor 2: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31995728
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032496 - response to lipopolysaccharide GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 256
+	Hs
		119204 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13
+	Hs
		119356 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82
+	Hs
		119341 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54
+	Hs
		119190 LEG9_HUMAN (1-355): 6.7e-144: 412: 100.00		PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25
+	Hs
		121115 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13
+	Hs
		121143 LEG8_HUMAN (1-355): 1.01e-104: 312: 30.85		PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54