Protein: NEB2
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)

Gene: NEB2, PPP1R9B
Organism: Homo sapiens
Interactions: 194
UniProt ID: Q96SB3

Gene Ontology (top 5):
GO:0000164 - protein phosphatase type 1 complex
GO:0001560 - regulation of cell growth by extracellular stimulus
GO:0001975 - response to amphetamine
GO:0003006 - developmental process involved in reproduction
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

786802

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

16

20

Small-scale

0.986

High

967935

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

13

20

Small-scale

0.983

High

968418

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

4

20

Small-scale

0.902

High

177403

ARHGB
Rho guanine nucleotide exchange factor 11

2

20

High-throughput

0.737

High

1092481

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

20

Small-scale

0.713

High

1402513

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.698

High

711399

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.691

High

955505

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.691

High

1402537

JIP1
C-Jun-amino-terminal kinase-interacting protein 1

1

16

High-throughput

0.691

High

169268

CASQ2
Calsequestrin-2

3

8

High-throughput

0.667

High

1399275

LRRC7
Leucine-rich repeat-containing protein 7

1

19

Small-scale

0.647

High

953051

ACTB
Actin, cytoplasmic 1

3

13

High-throughput

0.640

High

1160729

DREB
Drebrin

2

19

High-throughput

0.628

High

1140192

ARHG6
Rho guanine nucleotide exchange factor 6

1

15

High-throughput

0.618

High

1255171

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1396774

SNX27
Sorting nexin-27

1

18

High-throughput

0.618

High

1402531

ZO2
Tight junction protein 2

1

20

High-throughput

0.618

High

799419

BRCA1
Breast cancer type 1 susceptibility protein

2

6

High-throughput

0.611

High

1347145

WDR48
WD repeat-containing protein 48

2

7

High-throughput

0.611

High

572465

DRD2
D(2) dopamine receptor

2

20

Small-scale

0.606

High

342456

RPP29
Ribonuclease P protein subunit p29

2

0

High-throughput

0.602

High

582930

EZRI
Ezrin

2

20

High-throughput

0.584

High

1143489

PCM1
Pericentriolar material 1 protein

2

1

High-throughput

0.584

High

1402506

RING2
E3 ubiquitin-protein ligase RING2

2

12

High-throughput

0.584

High

1402525

ANLN
Anillin

2

10

High-throughput

0.584

High

928746

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

0

High-throughput

0.578

High

708865

PTN4
Tyrosine-protein phosphatase non-receptor type 4

1

20

High-throughput

0.575

High

842839

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

20

Small-scale

0.573

High

1217692

SYDE2
Rho GTPase-activating protein SYDE2

2

20

High-throughput

0.571

High

1227313

A16L1
Autophagy-related protein 16-1

2

16

High-throughput

0.571

High

442793

RB
Retinoblastoma-associated protein

1

2

Small-scale

0.561

High

683650

ITB8
Integrin beta-8

1

12

Small-scale

0.561

High

704986

RBL1
Retinoblastoma-like protein 1

1

2

Small-scale

0.561

High

1065678

RBL2
Retinoblastoma-like protein 2

1

2

Small-scale

0.561

High

1040898

MECOM
Histone-lysine N-methyltransferase MECOM

1

6

High-throughput

0.552

High

1402509

KXDL1
KxDL motif-containing protein 1

2

2

High-throughput

0.549

High

162265

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

1

High-throughput

0.536

High

176869

DCLK1
Serine/threonine-protein kinase DCLK1

1

20

High-throughput

0.536

High

224780

ACTN4
Alpha-actinin-4

1

20

High-throughput

0.536

High

340932

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

7

High-throughput

0.536

High

637695

FLNA
Filamin-A

1

20

High-throughput

0.536

High

718836

CCND2
G1/S-specific cyclin-D2

1

2

High-throughput

0.536

High

772970

MYH9
Myosin-9

1

9

High-throughput

0.536

High

862951

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

20

High-throughput

0.536

High

866796

CAZA2
F-actin-capping protein subunit alpha-2

1

4

High-throughput

0.536

High

867362

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

897369

CDK7
Cyclin-dependent kinase 7

1

3

High-throughput

0.536

High

967169

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

2

High-throughput

0.536

High

972529

RS14
Small ribosomal subunit protein uS11

1

2

High-throughput

0.536

High

986159

RL8
Large ribosomal subunit protein uL2

1

3

High-throughput

0.536

High

1052090

CALD1
Caldesmon

1

20

High-throughput

0.536

High

1124693

SRC8
Src substrate cortactin

1

18

High-throughput

0.536

High

1146461

KS6A2
Ribosomal protein S6 kinase alpha-2

1

20

High-throughput

0.536

High

1152213

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

High-throughput

0.536

High

1325438

SYNPO
Synaptopodin

1

17

High-throughput

0.536

High

1327403

DCLK2
Serine/threonine-protein kinase DCLK2

1

20

High-throughput

0.536

High

1330296

KC1AL
Casein kinase I isoform alpha-like

1

8

High-throughput

0.536

High

1352220

TBCK
TBC domain-containing protein kinase-like protein

1

20

High-throughput

0.536

High

1353783

HASP
Serine/threonine-protein kinase haspin

1

1

High-throughput

0.536

High

1368234

CDKL2
Cyclin-dependent kinase-like 2

1

10

High-throughput

0.536

High

1392655

MYO19
Unconventional myosin-XIX

1

19

High-throughput

0.536

High

1402514

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

4

High-throughput

0.536

High

1402519

CCD68
Coiled-coil domain-containing protein 68

1

1

High-throughput

0.536

High

1402524

PAK6
Serine/threonine-protein kinase PAK 6

1

10

High-throughput

0.536

High

1402527

SALL1
Sal-like protein 1

1

2

High-throughput

0.536

High

1402532

LIMA1
LIM domain and actin-binding protein 1

1

9

High-throughput

0.536

High

1402533

CYH4
Cytohesin-4

1

13

High-throughput

0.536

High

1402535

CSN3
COP9 signalosome complex subunit 3

1

1

High-throughput

0.536

High

221285

DCX
Neuronal migration protein doublecortin

2

9

Small-scale

0.533

High

569270

YJU2B
Probable splicing factor YJU2B

1

0

High-throughput

0.513

High

571785

FPPS
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.513

High

679240

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.513

High

1101238

NMI
N-myc-interactor

1

0

High-throughput

0.513

High

1357693

SNX33
Sorting nexin-33

1

0

High-throughput

0.513

High

1402508

CGRE1
Cell growth regulator with EF hand domain protein 1

1

0

High-throughput

0.513

High

1402512

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.513

High

1402521

CSTP1
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

1

0

High-throughput

0.513

High

477192

ADA2A
Alpha-2A adrenergic receptor

1

20

Small-scale

0.501

High

612347

ADA2B
Alpha-2B adrenergic receptor

1

20

Small-scale

0.501

High

616704

ADA2C
Alpha-2C adrenergic receptor

1

20

Small-scale

0.501

High

773777

ACTN2
Alpha-actinin-2

1

20

Small-scale

0.501

High

996523

ACTS
Actin, alpha skeletal muscle

1

13

Small-scale

0.501

High

1137470

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

471196

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

6

High-throughput

0.489

High

1164154

CP51A
Lanosterol 14-alpha demethylase

1

3

High-throughput

0.489

High

1402515

NUAK2
NUAK family SNF1-like kinase 2

1

12

High-throughput

0.489

High

567221

PPA5
Tartrate-resistant acid phosphatase type 5

1

0

High-throughput

0.481

High

134836

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.479

High

164420

NRP1
Neuropilin-1

1

7

High-throughput

0.479

High

177298

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

12

High-throughput

0.479

High

214909

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

5

High-throughput

0.479

High

248051

NUPR1
Nuclear protein 1

1

3

High-throughput

0.479

High

249508

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

1

High-throughput

0.479

High

323543

TRI37
E3 ubiquitin-protein ligase TRIM37

1

19

High-throughput

0.479

High

331250

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

346217

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

8

High-throughput

0.479

High

372914

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

390738

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

437312

K2C8
Keratin, type II cytoskeletal 8

1

6

High-throughput

0.479

High

560489

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

576672

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

8

High-throughput

0.479

High

584577

VAV
Proto-oncogene vav

1

20

High-throughput

0.479

High

605787

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

7

High-throughput

0.479

High

630187

ACM3
Muscarinic acetylcholine receptor M3

1

20

Small-scale

0.479

High

657661

GCSP
Glycine dehydrogenase

1

5

High-throughput

0.479

High

702036

TMOD1
Tropomodulin-1

1

3

High-throughput

0.479

High

732918

CCKAR
Cholecystokinin receptor type A

1

20

Small-scale

0.479

High

732940

GASR
Gastrin/cholecystokinin type B receptor

1

20

Small-scale

0.479

High

767489

RADI
Radixin

1

20

High-throughput

0.479

High

770826

ADA1B
Alpha-1B adrenergic receptor

1

20

Small-scale

0.479

High

774570

BASI
Basigin

1

20

High-throughput

0.479

High

831279

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

838948

RHG25
Rho GTPase-activating protein 25

1

17

High-throughput

0.479

High

854912

RECQ1
ATP-dependent DNA helicase Q1

1

10

High-throughput

0.479

High

872656

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

896619

VASP
Vasodilator-stimulated phosphoprotein

1

20

High-throughput

0.479

High

897949

CDK9
Cyclin-dependent kinase 9

1

9

High-throughput

0.479

High

930024

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

4

High-throughput

0.479

High

935957

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

6

High-throughput

0.479

High

977806

ACTA
Actin, aortic smooth muscle

1

13

High-throughput

0.479

High

990635

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

993300

ACTG
Actin, cytoplasmic 2

1

13

High-throughput

0.479

High

1031511

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.479

High

1035855

KIF23
Kinesin-like protein KIF23

1

20

High-throughput

0.479

High

1055846

RING1
E3 ubiquitin-protein ligase RING1

1

10

High-throughput

0.479

High

1060720

SOS2
Son of sevenless homolog 2

1

13

High-throughput

0.479

High

1105076

TCOF
Treacle protein

1

15

High-throughput

0.479

High

1109199

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

20

High-throughput

0.479

High

1114081

CUL3
Cullin-3

1

14

High-throughput

0.479

High

1119630

RGRF1
Ras-specific guanine nucleotide-releasing factor 1

1

20

Small-scale

0.479

High

1137963

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1140725

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.479

High

1142257

CD5R1
Cyclin-dependent kinase 5 activator 1

1

1

High-throughput

0.479

High

1153883

SMAD2
Mothers against decapentaplegic homolog 2

1

14

High-throughput

0.479

High

1156190

ZYX
Zyxin

1

14

High-throughput

0.479

High

1163664

PPR3A
Protein phosphatase 1 regulatory subunit 3A

1

3

High-throughput

0.479

High

1289560

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1291781

ARHGP
Rho guanine nucleotide exchange factor 25

1

20

High-throughput

0.479

High

1308811

NAV2
Neuron navigator 2

1

20

High-throughput

0.479

High

1324049

RHG24
Rho GTPase-activating protein 24

1

20

High-throughput

0.479

High

1339555

NEUA
N-acylneuraminate cytidylyltransferase

1

1

High-throughput

0.479

High

1356020

NOC3L
Nucleolar complex protein 3 homolog

1

1

High-throughput

0.479

High

1367082

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1400417

LMTK3
Serine/threonine-protein kinase LMTK3

1

20

High-throughput

0.479

High

1402510

OVOL2
Transcription factor Ovo-like 2

1

5

Small-scale

0.479

High

1402511

RHG09
Rho GTPase-activating protein 9

1

20

High-throughput

0.479

High

1402518

VP33B
Vacuolar protein sorting-associated protein 33B

1

3

High-throughput

0.479

High

1402520

CHM4B
Charged multivesicular body protein 4b

1

5

High-throughput

0.479

High

1402522

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

1402526

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1402528

RNF12
E3 ubiquitin-protein ligase RLIM

1

1

High-throughput

0.479

High

1402534

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.479

High

1402538

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

4

High-throughput

0.479

High

141063

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

188970

TMPS2
Transmembrane protease serine 2

1

0

High-throughput

0.458

High

400008

CATA
Catalase

1

0

High-throughput

0.458

High

693061

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

834131

IPP2
Protein phosphatase inhibitor 2

1

0

Small-scale

0.458

High

1117129

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

Small-scale

0.458

High

1117210

THOC5
THO complex subunit 5

1

0

High-throughput

0.458

High

1272250

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.458

High

1360920

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.458

High

1371353

TF3B
Transcription factor IIIB 90 kDa subunit

1

0

Small-scale

0.458

High

1402516

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

1402523

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

255179

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.445

High

324199

CE152
Centrosomal protein of 152 kDa

1

11

High-throughput

0.445

High

516577

CALM3
Calmodulin-3

1

1

High-throughput

0.445

High

530251

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.445

High

839075

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

5

High-throughput

0.445

High

987881

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.445

High

1103332

CTBP1
C-terminal-binding protein 1

1

7

High-throughput

0.445

High

1234916

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

1331745

CCD89
Coiled-coil domain-containing protein 89

1

9

High-throughput

0.445

High

1398330

CEP63
Centrosomal protein of 63 kDa

1

20

High-throughput

0.445

High

1402507

ZBT18
Zinc finger and BTB domain-containing protein 18

1

9

High-throughput

0.445

High

1402529

TEX10
Testis-expressed protein 10

1

1

High-throughput

0.445

High

1402536

COR2B
Coronin-2B

1

7

High-throughput

0.445

High

352521

TOP3B
DNA topoisomerase 3-beta-1

1

2

High-throughput

0.437

High

451436

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.437

High

460864

CATB
Cathepsin B

1

1

High-throughput

0.437

High

1027968

ECT2L
Epithelial cell-transforming sequence 2 oncogene-like

1

20

High-throughput

0.437

High

1251947

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.437

High

1368938

GOGA1
Golgin subfamily A member 1

1

13

High-throughput

0.437

High

1402530

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

2

High-throughput

0.437

High

1402539

CCD61
Centrosomal protein CCDC61

1

0

Small-scale

0.426

High

1387016

Q96D37
VAV1 protein

1

20

High-throughput

0.407

High

1402517

OSBL5
Oxysterol-binding protein-related protein 5

1

3

High-throughput

0.407

High

1196143

RM51
Large ribosomal subunit protein mL51

1

0

High-throughput

0.279

Low

1198842

ZC21C
Zinc finger C2HC domain-containing protein 1C

1

0

High-throughput

0.279

Low

1260405

H1FNT
Testis-specific H1 histone

1

0

High-throughput

0.279

Low

1395803

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.279

Low

1275485

TRM1L
tRNA

1

0

High-throughput

0.249

Low

1335509

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025