HitPredict

Interactor 1: SESD1 (Q80UK0)
SEC14 domain and spectrin repeat-containing protein 1 (Huntingtin-interacting protein-like protein)
Gene: Sestd1

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 696 Mm			1 1161
+	Mm
		1186645 ACTN1_MOUSE (356-684): 5.66e-18: 90.8: 13.37		TSC1_MOUSE (1-1161): 0: 771: 100.00
+	Hs
		521588 ACTN1_HUMAN (356-684): 5.37e-18: 90.8: 13.37		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Rn
		222475 KALRN_RAT (136-680): 1.84e-28: 124: 14.06		MRCKA_RAT (784-1161): 5.39e-22: 105: 10.71
+	Rn
		957077 KALRN_RAT (136-680): 1.84e-28: 124: 14.06		MRCKB_RAT (356-848): 5.48e-20: 98.7: 9.39
+	Hs
		148339 ACTN1_HUMAN (356-684): 5.37e-18: 90.8: 13.37		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148786 SPTN1_HUMAN (130-620): 5.85e-16: 84.6: 10.50		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148171 ACTN4_HUMAN (356-684): 3.26e-15: 81.9: 11.85		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		148722 ACTN3_HUMAN (356-684): 6.08e-15: 80.8: 11.71		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		521484 ACTN1_HUMAN (356-684): 5.37e-18: 90.8: 13.37		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		522612 SPTN1_HUMAN (130-620): 5.85e-16: 84.6: 10.50		MYH7_HUMAN (394-1133): 2.36e-26: 119: 8.63
+	Hs
		724817 SPTN1_HUMAN (130-620): 5.85e-16: 84.6: 10.50		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		149428 MACF1_HUMAN (157-518): 1.45e-11: 70.3: 11.78		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Hs
		211515 ACTN4_HUMAN (356-684): 3.26e-15: 81.9: 11.85		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		148463 ACTN2_HUMAN (269-681): 1.32e-10: 66.9: 10.61		CTRO_HUMAN (326-1095): 8.06e-30: 131: 10.51
+	Dm
		404218 ACTN_DROME (356-685): 4.05e-19: 94.2: 12.73		MYSA_DROME (405-1117): 3.26e-20: 99.9: 10.46
+	Hs
		110636 H3BPE1_HUMAN (157-518): 9.3e-12: 71.1: 11.78		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		725073 MACF1_HUMAN (157-518): 1.45e-11: 70.3: 11.78		MYH9_HUMAN (649-1160): 1.28e-25: 117: 10.68
+	Hs
		1045471 SPTN1_HUMAN (130-620): 5.85e-16: 84.6: 10.50		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Hs
		211632 ACTN4_HUMAN (356-684): 3.26e-15: 81.9: 11.85		MY18A_HUMAN (367-910): 1.36e-20: 101: 9.71
+	Dm
		527109 SPTCA_DROME (134-620): 4.23e-11: 68.8: 10.26		Q9VCC9_DROME (779-1108): 3.26e-09: 63.3: 9.67