Protein: CRY1
Cryptochrome-1 (DmCRY1) (dcry) (Blue light photoreceptor)

Gene: CRY1, cry
Organism: Drosophila melanogaster
Interactions: 127
UniProt ID: O77059

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

304944

TIM
Protein timeless

11

2

Small-scale

0.971

High

304907

PER
Period circadian protein

9

20

Small-scale

0.747

High

305010

Q9VMY0
Jetlag, isoform A

5

0

Small-scale

0.681

High

304914

ACT1
Actin-5C

2

1

Small-scale

0.620

High

304959

INAD
Inactivation-no-after-potential D protein

2

0

Small-scale

0.593

High

304992

Q9VC96
BRWD3

1

1

Small-scale

0.573

High

304965

Q7K511
D-2-hydroxyglutarate dehydrogenase, mitochondrial

2

0

High-throughput

0.559

High

304945

ACT3
Actin-57B

1

1

Small-scale

0.552

High

304913

NINAC
Neither inactivation nor afterpotential protein C

1

0

Small-scale

0.529

High

304909

CSK2A
Casein kinase II subunit alpha

1

2

High-throughput

0.515

High

56456

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

0

High-throughput

0.493

High

304920

SGG
Protein kinase shaggy

1

0

Small-scale

0.493

High

304979

FAXC
Failed axon connections

1

0

High-throughput

0.493

High

305006

FKB59
FK506-binding protein 59

1

0

High-throughput

0.493

High

305013

ACSA
Acetyl-coenzyme A synthetase

1

0

High-throughput

0.493

High

305020

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

304975

Q8SY07
PRKCA-binding protein

1

1

High-throughput

0.481

High

53455

PKN
Serine/threonine-protein kinase N

1

1

High-throughput

0.479

High

95316

E1JIM4
Mini spindles, isoform B

1

6

High-throughput

0.479

High

197203

RAB6
Ras-related protein Rab6

1

1

High-throughput

0.479

High

264577

KPYK
Pyruvate kinase

1

1

High-throughput

0.479

High

304903

EF1B
Probable elongation factor 1-beta

1

1

High-throughput

0.479

High

304906

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.479

High

304908

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.479

High

304911

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.479

High

304912

LAM0
Lamin Dm0

1

2

High-throughput

0.479

High

304926

DDX6
ATP-dependent RNA helicase me31b

1

7

Small-scale

0.479

High

304928

PPIA
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

304929

BRM
ATP-dependent helicase brm

1

1

High-throughput

0.479

High

304930

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

304932

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

304933

ARP3
Actin-related protein 3

1

2

High-throughput

0.479

High

304934

RFC1
Replication factor C subunit 1

1

1

High-throughput

0.479

High

304935

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

4

High-throughput

0.479

High

304938

LA
La protein homolog

1

4

High-throughput

0.479

High

304942

KL61
Kinesin-like protein Klp61F

1

1

High-throughput

0.479

High

304947

MLC2
Myosin-2 essential light chain

1

2

High-throughput

0.479

High

304950

CALM
Calmodulin

1

1

Small-scale

0.479

High

304957

MY31D
Unconventional myosin ID

1

1

High-throughput

0.479

High

304958

MY61F
Unconventional myosin IC

1

1

High-throughput

0.479

High

304960

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

1

High-throughput

0.479

High

304963

NLP
Nucleoplasmin-like protein

1

1

High-throughput

0.479

High

304971

Y8611
Probable ATP-dependent RNA helicase CG8611

1

7

High-throughput

0.479

High

304973

SLE
Protein slender lobes

1

1

High-throughput

0.479

High

304974

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.479

High

304982

XPO1
Exportin-1

1

4

High-throughput

0.479

High

304983

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

2

High-throughput

0.479

High

304984

PRDX2
Peroxiredoxin 2

1

2

High-throughput

0.479

High

304985

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

2

High-throughput

0.479

High

304986

THIO2
Thioredoxin-2

1

1

High-throughput

0.479

High

304990

LARP
La-related protein 1

1

2

High-throughput

0.479

High

304998

Y6693
J domain-containing protein CG6693

1

1

High-throughput

0.479

High

304999

MCM5
DNA replication licensing factor Mcm5

1

5

High-throughput

0.479

High

305000

RUVB1
RuvB-like helicase 1

1

3

High-throughput

0.479

High

305001

DDX3
ATP-dependent RNA helicase bel

1

6

Small-scale

0.479

High

305005

AURKB
Aurora kinase B

1

2

High-throughput

0.479

High

305012

DDX1
ATP-dependent RNA helicase Ddx1

1

7

High-throughput

0.479

High

305016

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

8

High-throughput

0.479

High

305017

RS10B
Small ribosomal subunit protein eS10B

1

1

High-throughput

0.479

High

304925

HMOC
Homeotic protein ocelliless

1

0

High-throughput

0.460

High

304996

Q9VE88
Uncharacterized protein, isoform B

1

0

High-throughput

0.460

High

56540

CLU
Protein clueless

1

0

High-throughput

0.458

High

234526

VINC
Vinculin

1

0

High-throughput

0.458

High

304904

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.458

High

304916

DCTN1
Dynactin subunit 1

1

0

High-throughput

0.458

High

304917

KINH
Kinesin heavy chain

1

0

High-throughput

0.458

High

304918

CATA
Catalase

1

0

High-throughput

0.458

High

304919

CRN
Protein crooked neck

1

0

High-throughput

0.458

High

304922

GNAI
G protein alpha i subunit

1

0

High-throughput

0.458

High

304923

NCD
Protein claret segregational

1

0

High-throughput

0.458

High

304924

CPD1
Chromosomal protein D1

1

0

High-throughput

0.458

High

304927

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

304936

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.458

High

304937

CDC42
Cdc42 homolog

1

0

High-throughput

0.458

High

304940

PEP
Zinc finger protein on ecdysone puffs

1

0

High-throughput

0.458

High

304941

MOEH
Moesin/ezrin/radixin homolog 1

1

0

High-throughput

0.458

High

304946

EAS
Ethanolamine kinase

1

0

High-throughput

0.458

High

304949

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.458

High

304954

HTS
Protein hu-li tai shao

1

0

High-throughput

0.458

High

304955

DGK2
Eye-specific diacylglycerol kinase

1

0

Small-scale

0.458

High

304962

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

304964

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.458

High

304968

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.458

High

304970

DCLK
Serine/threonine-protein kinase CG17528

1

0

High-throughput

0.458

High

304976

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

Small-scale

0.458

High

304980

MYSN
Myosin heavy chain, non-muscle

1

0

High-throughput

0.458

High

304981

ATRX
Transcriptional regulator ATRX homolog

1

0

High-throughput

0.458

High

304987

NU154
Nuclear pore complex protein Nup154

1

0

High-throughput

0.458

High

304989

INT11
Integrator complex subunit 11

1

0

High-throughput

0.458

High

304993

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

0

High-throughput

0.458

High

304994

EI3D1
Eukaryotic translation initiation factor 3 subunit D-1

1

0

High-throughput

0.458

High

304995

PINTA
Retinol-binding protein pinta

1

0

High-throughput

0.458

High

305002

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

305003

NOC3L
Nucleolar complex protein 3

1

0

High-throughput

0.458

High

305004

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

0

High-throughput

0.458

High

305007

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

305008

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

305014

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.458

High

305015

AGO2
Protein argonaute-2

1

0

High-throughput

0.458

High

305018

THOC5
THO complex subunit 5

1

0

High-throughput

0.458

High

304939

PNUT
Protein peanut

1

1

High-throughput

0.437

High

304948

SEPT2
Septin-2

1

1

High-throughput

0.437

High

304956

PCAT
Lysophosphatidylcholine acyltransferase

1

1

High-throughput

0.437

High

304967

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.437

High

304969

MMSA
Probable methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial

1

1

High-throughput

0.437

High

305009

C28D1
Probable cytochrome P450 28d1

1

1

High-throughput

0.437

High

68156

A8DY79
Bruchpilot, isoform G

1

0

Small-scale

0.288

High

304905

H3
Histone H3

1

0

High-throughput

0.249

Low

304910

RLA1
Large ribosomal subunit protein P1

1

0

High-throughput

0.249

Low

304915

LAMB1
Laminin subunit beta-1

1

0

High-throughput

0.249

Low

304921

SYB
Synaptobrevin

1

0

High-throughput

0.249

Low

304931

CALR
Calreticulin

1

0

High-throughput

0.249

Low

304943

RALA
Ras-related protein Ral-a

1

0

High-throughput

0.249

Low

304951

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

304952

CYC2
Cytochrome c-2

1

0

High-throughput

0.249

Low

304953

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.249

Low

304961

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.249

Low

304966

RS15B
Small ribosomal subunit protein uS8B

1

0

High-throughput

0.249

Low

304972

NOL6
Nucleolar protein 6

1

0

High-throughput

0.249

Low

304977

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.249

Low

304978

AT5F1
ATP synthase subunit b, mitochondrial

1

0

High-throughput

0.249

Low

304988

3HIDH
3-hydroxyisobutyrate dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

304991

UN13B
Protein unc-13 homolog 4B

1

0

High-throughput

0.249

Low

304997

RLP24
Probable ribosome biogenesis protein RLP24

1

0

High-throughput

0.249

Low

305011

EI3F1
Eukaryotic translation initiation factor 3 subunit F-1

1

0

High-throughput

0.249

Low

305019

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.249

Low

305021

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025