HitPredict

Interactor 1: FACD2 (Q80V62)
Fanconi anemia group D2 protein homolog (Protein FACD2)
Gene: Fancd2

Interactor 2: SMC1A (Q9CU62)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Chromosome segregation protein SmcB) (Sb1.8)
Gene: SMC1A

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28378742
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1450 Mm			1 1233
+	Hs
		1057382 FACD2_HUMAN (1-1440): 0: 1944: 74.93		SMC1A_HUMAN (1-1233): 1.18e-125: 419: 99.84
+	Hs
		1242600 FACD2_HUMAN (1-1440): 0: 1944: 74.93		SMC1B_HUMAN (1-1233): 3.31e-107: 368: 53.20
+	Mm
		1193753 FACD2_MOUSE (1-1438): 0: 1970: 100.00		SMC2_MOUSE (3-1214): 2.1e-72: 266: 18.28
+	Mm
		1194026 FACD2_MOUSE (1-1438): 0: 1970: 100.00		SMC3_MOUSE (3-1229): 7.9e-70: 258: 16.17
+	Hs
		311613 FACD2_HUMAN (1-1440): 0: 1944: 74.93		SMC2_HUMAN (3-1214): 7.15e-73: 267: 17.88
+	Hs
		1315878 FACD2_HUMAN (1-1440): 0: 1944: 74.93		SMC4_HUMAN (4-1216): 4.21e-71: 263: 20.18
+	Hs
		1315907 FACD2_HUMAN (1-1440): 0: 1944: 74.93		SMC3_HUMAN (3-1229): 1.16e-69: 258: 16.17
+	Mm
		1193842 FACD2_MOUSE (1-1438): 0: 1970: 100.00		MYH9_MOUSE (69-1026): 1.87e-44: 179: 9.42
+	Mm
		1143168 FACD2_MOUSE (1-1438): 0: 1970: 100.00		MYH10_MOUSE (612-1128): 3.92e-18: 92.9: 9.21
+	Mm
		93874 FACD2_MOUSE (1-1438): 0: 1970: 100.00		E9QPE7_MOUSE (49-618): 5.32e-16: 85.9: 10.45
+	Mm
		1132060 FACD2_MOUSE (1-1438): 0: 1970: 100.00		MYH1_MOUSE (783-1129): 4.88e-13: 76.3: 8.93
+	Hs
		724999 FACD2_HUMAN (1-1440): 0: 1944: 74.93		MYH9_HUMAN (591-1127): 4.05e-21: 102: 11.15