HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: RBM14 (Q96PK6)
RNA-binding protein 14 (Paraspeckle protein 2) (PSP2) (RNA-binding motif protein 14) (RRM-containing coactivator activator/modulator) (Synaptotagmin-interacting protein) (SYT-interacting protein)
Gene: RBM14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26725010
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 669
+	Hs
		1194271 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		MSI2H_HUMAN (2-292): 1.09e-51: 183: 18.01
+	Hs
		550310 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP1_HUMAN (3-555): 1.63e-35: 144: 14.36
+	Hs
		1120181 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		HNRPD_HUMAN (76-161): 1.03e-15: 81.2: 22.45
+	Hs
		1101980 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP4_HUMAN (71-151): 5.62e-10: 64.6: 23.60
+	Hs
		1194132 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PAP1L_HUMAN (71-151): 1.61e-09: 63.1: 20.23
+	Hs
		1194374 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP3_HUMAN (71-151): 1.86e-09: 62.7: 21.35
+	At
		306156 LRP6B_ARATH (2-265): 6.45e-54: 194: 21.20		PABP2_ARATH (3-494): 2.65e-28: 122: 12.74
+	Hs
		550464 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PABP1_HUMAN (3-555): 1.63e-35: 144: 14.36
+	Hs
		550262 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PABP1_HUMAN (3-555): 1.63e-35: 144: 14.36
+	Hs
		550097 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		PABP1_HUMAN (3-555): 1.63e-35: 144: 14.36
+	At
		842070 LRP6C_ARATH (12-249): 1.54e-49: 179: 23.14		PABP2_ARATH (3-494): 2.65e-28: 122: 12.74
+	Hs
		1102056 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PABP5_HUMAN (3-169): 2.17e-17: 86.5: 26.53
+	Hs
		431125 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		HNRPD_HUMAN (76-161): 1.03e-15: 81.2: 22.45
+	Hs
		1090216 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		550250 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		ELAV2_HUMAN (4-154): 1.38e-16: 83.8: 25.15
+	Hs
		506129 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PAB4L_HUMAN (75-150): 2.23e-11: 68.1: 25.00
+	Hs
		1102095 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PABP4_HUMAN (71-151): 5.62e-10: 64.6: 23.60
+	Hs
		431115 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		PABP4_HUMAN (71-151): 5.62e-10: 64.6: 23.60
+	Hs
		1197178 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PAP1L_HUMAN (71-151): 1.61e-09: 63.1: 20.23