Protein: ECE1
Endothelin-converting enzyme 1 (ECE-1) (EC 3.4.24.71)

Gene: ECE1
Organism: Homo sapiens
Interactions: 88
UniProt ID: P42892

Gene Ontology (top 5):
GO:0001921 - positive regulation of receptor recycling
GO:0003100 - regulation of systemic arterial blood pressure by endothelin
GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005765 - lysosomal membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

318358

ECEL1
Endothelin-converting enzyme-like 1

1

1

High-throughput

0.691

High

572312

LEG3
Galectin-3

3

4

Small-scale

0.667

High

654141

CALX
Calnexin

3

4

High-throughput

0.650

High

792191

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

0

High-throughput

0.638

High

121124

LEG8
Galectin-8

2

4

High-throughput

0.628

High

792175

CLK2
Dual specificity protein kinase CLK2

3

1

High-throughput

0.616

High

597148

FUT3
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3

2

0

High-throughput

0.602

High

792197

SUSD4
Sushi domain-containing protein 4

2

0

High-throughput

0.602

High

792207

NPB
Neuropeptide B

2

0

High-throughput

0.602

High

792186

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.584

High

67002

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.580

High

119230

LEG9
Galectin-9

2

4

High-throughput

0.574

High

506911

LAMP1
Lysosome-associated membrane glycoprotein 1

2

1

High-throughput

0.571

High

792182

KR108
Keratin-associated protein 10-8

2

5

High-throughput

0.553

High

792205

KRA13
Keratin-associated protein 1-3

2

3

High-throughput

0.553

High

382586

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

10

High-throughput

0.536

High

449216

LEG1
Galectin-1

1

4

High-throughput

0.536

High

532908

PRG2
Bone marrow proteoglycan

1

1

High-throughput

0.536

High

570309

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

4

High-throughput

0.536

High

588754

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

9

High-throughput

0.536

High

661083

CD1B
T-cell surface glycoprotein CD1b

1

9

High-throughput

0.536

High

685220

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

2

High-throughput

0.536

High

792188

PTC1
Protein patched homolog 1

1

1

High-throughput

0.536

High

792189

LRC32
Transforming growth factor beta activator LRRC32

1

1

High-throughput

0.536

High

792194

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.536

High

792210

CLC2B
C-type lectin domain family 2 member B

1

4

High-throughput

0.536

High

792212

T106A
Transmembrane protein 106A

1

2

High-throughput

0.536

High

792220

FBX6
F-box only protein 6

2

2

High-throughput

0.533

High

177835

TMPS2
Transmembrane protease serine 2

1

3

High-throughput

0.515

High

158913

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.513

High

526882

TDGF1
Protein Cripto

1

0

High-throughput

0.513

High

557063

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

792193

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

792200

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.513

High

792204

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

792206

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.513

High

792211

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

792215

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

792218

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.513

High

792219

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

792227

PCDA9
Protocadherin alpha-9

1

0

High-throughput

0.513

High

792228

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

344367

ANGT
Angiotensinogen

1

2

Small-scale

0.501

High

345178

KNG1
Kininogen-1

1

3

Small-scale

0.501

High

161036

CLGN
Calmegin

1

4

High-throughput

0.489

High

389445

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

792216

CST11
Cystatin-11

1

3

High-throughput

0.489

High

792224

FBX2
F-box only protein 2

1

2

High-throughput

0.489

High

792173

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.486

High

205142

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

348557

RASN
GTPase NRas

1

4

High-throughput

0.479

High

591761

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

592140

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

792176

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.479

High

792177

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

792178

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.479

High

792179

RAB25
Ras-related protein Rab-25

1

3

High-throughput

0.479

High

792184

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.479

High

792192

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

792199

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

792202

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

792203

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.479

High

792208

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

792221

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.479

High

792222

T106B
Transmembrane protein 106B

1

2

High-throughput

0.479

High

792225

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

792181

KR105
Keratin-associated protein 10-5

1

5

High-throughput

0.470

High

792214

MYOC
Myocilin

1

0

Small-scale

0.460

High

178424

STX7
Syntaxin-7

1

0

High-throughput

0.458

High

792183

RAC3
Ras-related C3 botulinum toxin substrate 3

1

0

High-throughput

0.458

High

792185

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

792187

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

792223

ANFY1
Rabankyrin-5

1

0

High-throughput

0.458

High

792174

CLK1
Dual specificity protein kinase CLK1

1

1

High-throughput

0.457

High

792180

KR101
Keratin-associated protein 10-1

1

5

High-throughput

0.439

High

372889

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.426

High

180118

SIA8E
Alpha-2,8-sialyltransferase 8E

1

0

High-throughput

0.279

Low

514353

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

792190

EP3A
Epididymal secretory protein E3-alpha

1

0

High-throughput

0.279

Low

792201

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

792209

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.279

Low

792213

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

792217

CG069
Putative uncharacterized protein PKD1L1-AS1

1

0

High-throughput

0.279

Low

420777

CALCA
Calcitonin gene-related peptide 1

1

0

Small-scale

0.261

Low

792196

MIDN
Midnolin

1

0

High-throughput

0.249

Low

792198

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

792226

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

792195

DB109
Putative beta-defensin 109B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024