Interactor 1: LRC8A (Q80WG5)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (Protein ebouriffe) (ebo)
Gene: Lrrc8a

Interactor 2: LRC8C (Q8R502)
Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)
Gene: Lrrc8c

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.584

The method score is based on:

Property Details
Experiments 29769723
Identification Methods 3D electron microscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_1~LRR_8, LRR_8~LRR_8, Pannexin_like~Pannexin_like
Common GO terms GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0015734 - taurine transmembrane transport
GO:0015810 - aspartate transmembrane transport
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 810
Mm

1 803
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Hs
+ At
+ At
+ Hs
+ At
+ At
+ At
+ At

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Last updated: 15 Jul 2024