HitPredict

Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: EMSY (Q8BMB0)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23395962, 23892456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 305 Mm			1 1264
+	Mm
		1113235 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		Q3USB6_MOUSE (769-857): 3.07e-20: 89.4: 82.52
+	Mm
		101829 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		F8WI37_MOUSE (28-802): 1.17e-11: 72.1: 8.88
+	Mm
		1194614 NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00		KMT2C_MOUSE (28-802): 1.17e-11: 72.1: 8.88
+	Hs
		858119 NKX25_HUMAN (23-164): 7.6e-43: 151: 29.45		CIC_HUMAN (60-1074): 5.12e-21: 102: 9.72
+	Hs
		858125 NKX25_HUMAN (23-164): 7.6e-43: 151: 29.45		SRRM2_HUMAN (119-1240): 1.72e-16: 87.9: 8.82
+	Hs
		620192 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		CIC_HUMAN (60-1074): 5.12e-21: 102: 9.72
+	Hs
		679158 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		CIC_HUMAN (60-1074): 5.12e-21: 102: 9.72
+	Hs
		941948 PITX1_HUMAN (35-289): 2.68e-34: 128: 15.88		CIC_HUMAN (60-1074): 5.12e-21: 102: 9.72
+	Hs
		1263870 NANOG_HUMAN (1-302): 7.54e-43: 150: 53.72		MUC16_HUMAN (42-551): 2.06e-13: 77.8: 14.07
+	Hs
		1300937 NKX24_HUMAN (3-166): 8.21e-32: 123: 28.66		CIC_HUMAN (60-1074): 5.12e-21: 102: 9.72
+	Hs
		620250 PAX3_HUMAN (70-257): 1.43e-30: 121: 18.04		CIC_HUMAN (60-1074): 5.12e-21: 102: 9.72
+	Mm
		976069 MSX2_MOUSE (47-193): 9.48e-32: 120: 27.21		MINT_MOUSE (58-1254): 3.15e-19: 96.8: 10.45
+	Hs
		620175 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		KMT2C_HUMAN (327-1134): 4.99e-11: 69.8: 7.72
+	Hs
		679137 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		KMT2C_HUMAN (327-1134): 4.99e-11: 69.8: 7.72
+	Hs
		658629 MSX1_HUMAN (4-185): 2.74e-36: 133: 29.19		CBP_HUMAN (172-435): 7.34e-09: 62.8: 20.65
+	Hs
		152588 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		KMT2D_HUMAN (114-974): 9.72e-10: 65.6: 8.73
+	Hs
		152596 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		KMT2D_HUMAN (114-974): 9.72e-10: 65.6: 8.73
+	Hs
		620186 PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81		CBP_HUMAN (172-435): 7.34e-09: 62.8: 20.65
+	Hs
		679149 TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80		CBP_HUMAN (172-435): 7.34e-09: 62.8: 20.65
+	Hs
		152615 LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49		KMT2D_HUMAN (114-974): 9.72e-10: 65.6: 8.73