Interactor 1: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Interactor 2: REST (Q8VIG1)
RE1-silencing transcription factor (Neural-restrictive silencer factor)
Gene: REST

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 0.60 0.554

The method score is based on:

Property Details
Experiments 17093407
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
and 8 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 305
Mm

1 1082
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs

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Last updated: 15 Jul 2024