HitPredict

Interactor 1: PAN2 (Q504Q3)
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (EC 3.1.13.4) (Inactive ubiquitin carboxyl-terminal hydrolase 52) (PAB1P-dependent poly(A)-specific ribonuclease) (Poly(A)-nuclease deadenylation complex subunit 2) (PAN deadenylation complex subunit 2)
Gene: PAN2

Interactor 2: TNR6C (Q9HCJ0)
Trinucleotide repeat-containing gene 6C protein
Gene: TNRC6C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.890

Property	Details
Experiments	21984184, 21981923, 29395067, 21984185
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PAN2_N~RRM_1
Common GO terms	GO:0000932 - P-body GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1202 Hs			1 1936
+	Hs
		1197529 PAN2_HUMAN (1-1202): 0: 1135: 100.00		TNR6A_HUMAN (2-1933): 6.2e-125: 439: 35.33
+	Hs
		1197597 PAN2_HUMAN (1-1202): 0: 1135: 100.00		TNR6B_HUMAN (18-1920): 5.08e-117: 413: 30.65
+	Hs
		1197598 PAN2_HUMAN (1-1202): 0: 1135: 100.00		SRRM2_HUMAN (858-1774): 6.45e-11: 70.1: 9.88
+	Dm
		53226 PAN2_DROME (5-1183): 0: 823: 38.84		GAWKY_DROME (650-1849): 7.25e-73: 271: 21.24
+	Hs
		1371620 UBP7_HUMAN (340-1038): 3.3e-89: 314: 12.02		CIC_HUMAN (47-1749): 1.24e-56: 220: 9.19
+	Hs
		828260 UBP8_HUMAN (411-854): 2.87e-79: 285: 11.25		MUC12_HUMAN (114-1775): 3.41e-55: 216: 9.35
+	Hs
		1371785 UBP7_HUMAN (340-1038): 3.3e-89: 314: 12.02		SRRM2_HUMAN (858-1774): 6.45e-11: 70.1: 9.88