HitPredict

Interactor 1: PCGF5 (Q86SE9)
Polycomb group RING finger protein 5 (RING finger protein 159)
Gene: PCGF5

Interactor 2: LMBL2 (Q969R5)
Lethal(3)malignant brain tumor-like protein 2 (H-l(3)mbt-like protein 2) (L(3)mbt-like protein 2)
Gene: L3MBTL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 256 Hs			1 705
+	Hs
		718083 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		718416 PCGF2_HUMAN (1-244): 2.94e-56: 185: 29.13		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1108529 PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1282142 PCGF6_HUMAN (4-248): 2.54e-43: 151: 32.25		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1282132 RING2_HUMAN (2-252): 1.71e-41: 146: 17.59		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Hs
		1282139 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		LMBL2_HUMAN (1-705): 0: 1012: 100.00
+	Mm
		886509 RING2_MOUSE (2-252): 2.64e-41: 146: 17.59		LMBL2_MOUSE (1-705): 0: 1001: 90.92
+	Mm
		1160052 RING2_MOUSE (2-252): 2.64e-41: 146: 17.59		MBTD1_MOUSE (64-604): 0: 756: 61.14
+	Hs
		1197578 PCGF5_HUMAN (1-256): 3.16e-62: 197: 100.00		SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03
+	Hs
		718098 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03
+	Hs
		718330 BMI1_HUMAN (1-229): 2.24e-57: 187: 30.38		SCML2_HUMAN (159-392): 8.81e-79: 267: 25.96
+	Hs
		718418 PCGF2_HUMAN (1-244): 2.94e-56: 185: 29.13		SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03
+	Hs
		1108531 PCGF3_HUMAN (3-255): 1.23e-48: 162: 37.04		SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03
+	Dm
		627170 SUZ2_DROME (9-226): 2.21e-46: 167: 26.13		SCM_DROME (397-697): 1.12e-74: 260: 26.06
+	Dm
		728808 PSC_DROME (2-252): 3.97e-46: 166: 25.39		SCM_DROME (397-697): 1.12e-74: 260: 26.06
+	Mm
		1225135 RING2_MOUSE (2-252): 2.64e-41: 146: 17.59		SCMH1_MOUSE (167-394): 1.83e-78: 267: 28.57
+	Hs
		1292153 PCGF1_HUMAN (4-232): 3.33e-42: 146: 31.06		SCMH1_HUMAN (167-402): 7.35e-79: 267: 28.03
+	Dm
		627172 SUZ2_DROME (9-226): 2.21e-46: 167: 26.13		SMBT_DROME (138-401): 4.84e-35: 145: 21.17
+	Dm
		728810 PSC_DROME (2-252): 3.97e-46: 166: 25.39		SMBT_DROME (138-401): 4.84e-35: 145: 21.17
+	Mm
		1207468 RING2_MOUSE (2-252): 2.64e-41: 146: 17.59		Q8BYC8_MOUSE (130-283): 1.63e-18: 92.2: 20.37