HitPredict

Interactor 1: NEK8 (Q86SG6)
Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8) (Nima-related protein kinase 12a)
Gene: NEK8

Interactor 2: NUDC2 (Q8WVJ2)
NudC domain-containing protein 2
Gene: NUDCD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26638075, 32707033, 25036637
Identification Methods	proximity labelling technology, affinity chromatography technology, pull down, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 692 Hs			1 157
+	Hs
		1197690 NEK8_HUMAN (1-692): 0: 727: 100.00		NUDC_HUMAN (16-142): 2.95e-46: 155: 21.21
+	Hs
		1197670 NEK8_HUMAN (1-692): 0: 727: 100.00		NUDC3_HUMAN (17-132): 9.89e-29: 109: 21.49
+	Hs
		1254356 NEK9_HUMAN (3-689): 0: 603: 34.37		NUDC2_HUMAN (1-157): 2.17e-77: 228: 100.00
+	Hs
		1065047 HERC3_HUMAN (278-636): 6.62e-79: 274: 24.55		NUDC2_HUMAN (1-157): 2.17e-77: 228: 100.00
+	Hs
		1039020 KCC2G_HUMAN (2-401): 7.59e-121: 373: 23.80		NUDC1_HUMAN (16-135): 7.3e-34: 126: 20.16
+	Hs
		89946 D6R938_HUMAN (2-364): 1.56e-119: 368: 22.49		NUDC1_HUMAN (16-135): 7.3e-34: 126: 20.16
+	Hs
		319943 HERC2_HUMAN (314-460): 2.25e-09: 63.2: 31.68		NUDC2_HUMAN (1-157): 2.17e-77: 228: 100.00