HitPredict

Interactor 1: SDCG8 (Q86SQ7)
Serologically defined colon cancer antigen 8 (Antigen NY-CO-8) (Centrosomal colon cancer autoantigen protein) (hCCCAP)
Gene: SDCCAG8

Interactor 2: RABE2 (Q9H5N1)
Rab GTPase-binding effector protein 2 (Rabaptin-5beta)
Gene: RABEP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.618

Property	Details
Experiments	33961781, 27224062
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0030030 - cell projection organization GO:0036064 - ciliary basal body GO:1902017 - regulation of cilium assembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 713 Hs			1 569
+	Hs
		1061879 SLMAP_HUMAN (70-641): 2.52e-42: 166: 16.87		RABE2_HUMAN (1-569): 6.14e-44: 166: 100.00
+	Hs
		1137871 MRCKA_HUMAN (247-703): 4.76e-46: 179: 16.22		MRCKA_HUMAN (241-552): 1.9e-37: 150: 16.30
+	Hs
		1061837 SLMAP_HUMAN (70-641): 2.52e-42: 166: 16.87		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		725191 SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00		MYH10_HUMAN (1-396): 3.25e-13: 74.9: 11.34
+	Rn
		222476 MRCKA_RAT (247-703): 1.84e-48: 186: 16.22		MRCKB_RAT (1-547): 3.27e-15: 81.6: 12.95
+	Hs
		724899 SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00		MYH9_HUMAN (184-568): 1.78e-11: 69.5: 10.80
+	Hs
		1189773 SDCG8_HUMAN (1-713): 1.5e-53: 198: 100.00		MYH14_HUMAN (7-532): 1.97e-11: 69.3: 15.53
+	Hs
		1137917 MRCKA_HUMAN (247-703): 4.76e-46: 179: 16.22		MRCKB_HUMAN (10-470): 3.13e-12: 72: 14.20
+	Rn
		222472 MRCKA_RAT (247-703): 1.84e-48: 186: 16.22		MRCKA_RAT (8-487): 6.62e-09: 61.2: 15.14
+	Hs
		528432 MYH13_HUMAN (2-595): 9.82e-21: 100: 8.85		MYH8_HUMAN (104-568): 1.89e-16: 85.3: 11.39
+	Hs
		528356 MYH6_HUMAN (2-562): 4.09e-20: 98.2: 10.60		MYH6_HUMAN (144-565): 1.4e-12: 73: 11.22
+	Rn
		361106 MYH6_RAT (2-562): 3.27e-20: 98.2: 11.39		MYH6_RAT (144-565): 2.28e-12: 72.2: 10.35
+	Hs
		725097 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH11_HUMAN (6-402): 2.94e-14: 78.4: 12.32
+	Mm
		93570 DESP_MOUSE (6-575): 9.06e-17: 87.3: 12.67		MYH9_MOUSE (140-564): 5.13e-15: 80.7: 11.92
+	Hs
		725095 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH10_HUMAN (1-396): 3.25e-13: 74.9: 11.34
+	Hs
		502901 MYH6_HUMAN (2-562): 4.09e-20: 98.2: 10.60		MYH3_HUMAN (155-565): 8.31e-10: 64.2: 11.43
+	Hs
		724687 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH9_HUMAN (184-568): 1.78e-11: 69.5: 10.80
+	Hs
		725189 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		MYH14_HUMAN (7-532): 1.97e-11: 69.3: 15.53
+	Hs
		148461 MYH10_HUMAN (256-708): 1.45e-17: 89.7: 12.64		CTRO_HUMAN (12-552): 8.68e-10: 63.9: 12.79
+	Rn
		92843 ROCK2_RAT (153-707): 4.91e-16: 84.8: 12.41		CTRO_RAT (9-479): 5.3e-09: 61.6: 12.08