Protein: S39A5
Zinc transporter ZIP5 (Solute carrier family 39 member 5) (Zrt- and Irt-like protein 5) (ZIP-5)

Gene: S39A5, SLC39A5
Organism: Homo sapiens
Interactions: 117
UniProt ID: Q6ZMH5

Gene Ontology (top 5):
GO:0001654 - eye development
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005886 - plasma membrane
GO:0006829 - zinc ion transport
GO:0016323 - basolateral plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1105207

S39A6
Zinc transporter ZIP6

3

8

High-throughput

0.855

High

1251819

S39AA
Zinc transporter ZIP10

2

8

High-throughput

0.811

High

1251772

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

3

2

High-throughput

0.662

High

1251798

ULBP3
UL16-binding protein 3

3

20

High-throughput

0.662

High

1251815

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

3

4

High-throughput

0.662

High

834676

TNFL9
Tumor necrosis factor ligand superfamily member 9

3

0

High-throughput

0.634

High

560979

GP1BB
Platelet glycoprotein Ib beta chain

2

6

High-throughput

0.628

High

607603

PTN2
Tyrosine-protein phosphatase non-receptor type 2

2

12

High-throughput

0.628

High

648564

FGFR4
Fibroblast growth factor receptor 4

2

15

High-throughput

0.628

High

761248

RYK
Tyrosine-protein kinase RYK

2

7

High-throughput

0.628

High

1022887

EFNB1
Ephrin-B1

2

3

High-throughput

0.628

High

1102716

PTPRS
Receptor-type tyrosine-protein phosphatase S

2

3

High-throughput

0.628

High

1157364

EXT1
Exostosin-1

2

12

High-throughput

0.628

High

1195218

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

2

3

High-throughput

0.628

High

1251768

LRP10
Low-density lipoprotein receptor-related protein 10

2

6

High-throughput

0.628

High

1251786

C1GLC
C1GALT1-specific chaperone 1

2

20

High-throughput

0.628

High

1251806

GOLP3
Golgi phosphoprotein 3

2

1

High-throughput

0.628

High

1206075

TGO1
Transport and Golgi organization protein 1 homolog

3

10

High-throughput

0.604

High

1251801

METL9
Protein-L-histidine N-pros-methyltransferase

3

7

High-throughput

0.604

High

1251805

GLP3L
Golgi phosphoprotein 3-like

3

1

High-throughput

0.604

High

1089110

HYAL2
Hyaluronidase-2

2

0

High-throughput

0.602

High

1251802

CYTM1
Cysteine-rich and transmembrane domain-containing protein 1

2

0

High-throughput

0.602

High

230808

EXTL3
Exostosin-like 3

2

12

High-throughput

0.601

High

1251800

ULBP1
UL16-binding protein 1

2

19

High-throughput

0.601

High

1242832

S39A4
Zinc transporter ZIP4

1

8

High-throughput

0.575

High

1241198

CC033
Protein C3orf33

2

5

High-throughput

0.574

High

1251767

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

2

High-throughput

0.574

High

1251775

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

2

2

High-throughput

0.574

High

1251780

NAT14
Probable N-acetyltransferase 14

2

1

High-throughput

0.574

High

1251787

SREC2
Scavenger receptor class F member 2

2

5

High-throughput

0.574

High

1251791

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

2

4

High-throughput

0.574

High

1251796

ABHEA
Protein ABHD14A

2

2

High-throughput

0.574

High

1251803

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

2

5

High-throughput

0.574

High

1251808

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

2

1

High-throughput

0.574

High

1251817

EXTL2
Exostosin-like 2

2

12

High-throughput

0.574

High

409428

HLAA
HLA class I histocompatibility antigen, A alpha chain

2

13

High-throughput

0.571

High

536262

PPAL
Lysosomal acid phosphatase

1

2

High-throughput

0.536

High

1251784

S67A1
Solute carrier family 67 member A1

1

9

High-throughput

0.536

High

1251794

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

5

High-throughput

0.536

High

1251799

ULBP2
UL16-binding protein 2

1

19

High-throughput

0.536

High

506612

GPHRB
Golgi pH regulator B

2

3

High-throughput

0.533

High

85373

GPHRA
Golgi pH regulator A

2

3

High-throughput

0.504

High

1251789

MIA2
Melanoma inhibitory activity protein 2

2

12

High-throughput

0.504

High

1251771

CHSS1
Chondroitin sulfate synthase 1

1

20

High-throughput

0.489

High

1251773

ARL10
ADP-ribosylation factor-like protein 10

1

10

High-throughput

0.489

High

249253

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

10

High-throughput

0.445

High

316516

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

7

High-throughput

0.445

High

363456

EGFR
Epidermal growth factor receptor

1

16

High-throughput

0.445

High

409585

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

13

High-throughput

0.445

High

520894

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

13

High-throughput

0.445

High

564833

NCAM1
Neural cell adhesion molecule 1

1

3

High-throughput

0.445

High

568068

HLAE
HLA class I histocompatibility antigen, alpha chain E

1

13

High-throughput

0.445

High

596576

EPCAM
Epithelial cell adhesion molecule

1

3

High-throughput

0.445

High

627537

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

15

High-throughput

0.445

High

764847

CTNB1
Catenin beta-1

1

2

High-throughput

0.445

High

787412

TGFR1
TGF-beta receptor type-1

1

3

High-throughput

0.445

High

1039958

AKA12
A-kinase anchor protein 12

1

3

High-throughput

0.445

High

1047593

NOTC2
Neurogenic locus notch homolog protein 2

1

4

High-throughput

0.445

High

1101741

PTK7
Inactive tyrosine-protein kinase 7

1

10

High-throughput

0.445

High

1102853

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.445

High

1107849

SQSTM
Sequestosome-1

1

1

High-throughput

0.445

High

1128521

DSC3
Desmocollin-3

1

7

High-throughput

0.445

High

1177154

MICB
MHC class I polypeptide-related sequence B

1

17

High-throughput

0.445

High

1251776

TIP
T-cell immunomodulatory protein

1

1

High-throughput

0.445

High

1251782

EXT2
Exostosin-2

1

12

High-throughput

0.445

High

1251790

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.445

High

1251792

CQ080
Mitochondrial nucleoid-associated protein 1

1

3

High-throughput

0.445

High

1251809

ITM2C
Integral membrane protein 2C

1

1

High-throughput

0.445

High

1251810

T106B
Transmembrane protein 106B

1

7

High-throughput

0.445

High

1251814

PDXL2
Podocalyxin-like protein 2

1

1

High-throughput

0.445

High

187988

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

0

High-throughput

0.426

High

1111055

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.426

High

1251769

SYT9
Synaptotagmin-9

1

0

High-throughput

0.426

High

1251793

INP5K
Inositol polyphosphate 5-phosphatase K

1

0

High-throughput

0.426

High

1251797

TMM59
Transmembrane protein 59

1

0

High-throughput

0.426

High

129871

GET1
Guided entry of tail-anchored proteins factor 1

1

2

High-throughput

0.407

High

165052

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

4

High-throughput

0.407

High

170829

CLGN
Calmegin

1

6

High-throughput

0.407

High

269870

IGSF3
Immunoglobulin superfamily member 3

1

2

High-throughput

0.407

High

327325

ZFPL1
Zinc finger protein-like 1

1

7

High-throughput

0.407

High

380761

HBD
Hemoglobin subunit delta

1

3

High-throughput

0.407

High

709132

TPP2
Tripeptidyl-peptidase 2

1

4

High-throughput

0.407

High

1081702

CGNL1
Cingulin-like protein 1

1

7

High-throughput

0.407

High

1094694

CAF1A
Chromatin assembly factor 1 subunit A

1

5

High-throughput

0.407

High

1094777

CAF1B
Chromatin assembly factor 1 subunit B

1

2

High-throughput

0.407

High

1105490

OS9
Protein OS-9

1

2

High-throughput

0.407

High

1217308

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

1

8

High-throughput

0.407

High

1218266

DIK1B
Divergent protein kinase domain 1B

1

5

High-throughput

0.407

High

1237864

MYORG
Myogenesis-regulating glycosidase

1

1

High-throughput

0.407

High

1251770

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

4

High-throughput

0.407

High

1251774

NETO2
Neuropilin and tolloid-like protein 2

1

3

High-throughput

0.407

High

1251777

GOGA5
Golgin subfamily A member 5

1

15

High-throughput

0.407

High

1251779

NEUFC
Neuferricin

1

2

High-throughput

0.407

High

1251781

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

14

High-throughput

0.407

High

1251783

FKB10
Peptidyl-prolyl cis-trans isomerase FKBP10

1

3

High-throughput

0.407

High

1251785

ERLEC
Endoplasmic reticulum lectin 1

1

2

High-throughput

0.407

High

1251788

FACR2
Fatty acyl-CoA reductase 2

1

5

High-throughput

0.407

High

1251807

SEC12
Guanine nucleotide-exchange factor SEC12

1

5

High-throughput

0.407

High

1251811

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

1

High-throughput

0.407

High

1251812

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.407

High

1251813

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

5

High-throughput

0.407

High

1251816

CHPF2
Chondroitin sulfate glucuronyltransferase

1

20

High-throughput

0.407

High

1251818

SE1L1
Protein sel-1 homolog 1

1

3

High-throughput

0.407

High

1251820

SIAT9
Lactosylceramide alpha-2,3-sialyltransferase

1

4

High-throughput

0.407

High

1251821

DJC16
DnaJ homolog subfamily C member 16

1

11

High-throughput

0.407

High

71344

F1712
Protein FAM171A2

3

0

High-throughput

0.345

High

49452

TM223
Transmembrane protein 223

2

0

High-throughput

0.328

High

1251778

CHPT1
Cholinephosphotransferase 1

2

0

High-throughput

0.328

High

1211823

AXDN1
Axonemal dynein light chain domain-containing protein 1

1

0

High-throughput

0.279

Low

162103

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.232

Low

244718

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.232

Low

351124

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.232

Low

854874

RECQ1
ATP-dependent DNA helicase Q1

1

0

High-throughput

0.232

Low

1154242

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.232

Low

1245375

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

High-throughput

0.232

Low

1251795

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.232

Low

1251804

ARV1
Protein ARV1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025