HitPredict

Interactor 1: ARVC (O00192)
Splicing regulator ARVCF (Armadillo repeat protein deleted in velo-cardio-facial syndrome)
Gene: ARVCF

Interactor 2: CTNA3 (Q9UI47)
Catenin alpha-3 (Alpha T-catenin) (Cadherin-associated protein)
Gene: CTNNA3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005912 - adherens junction GO:0045296 - cadherin binding GO:0098609 - cell-cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 962 Hs			1 895
+	Hs
		239222 CTND1_HUMAN (1-933): 0: 750: 46.14		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		239065 CTND1_HUMAN (1-933): 0: 750: 46.14		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		1355724 PKP3_HUMAN (19-852): 9.74e-160: 491: 26.20		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		1307400 PKP2_HUMAN (21-861): 8.39e-150: 468: 24.17		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		716759 PKP2_HUMAN (21-861): 8.39e-150: 468: 24.17		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Ce
		954162 JAC1_CAEEL (71-962): 5.82e-167: 523: 26.06		HMP1_CAEEL (9-894): 0: 808: 36.54
+	Dm
		578618 ARM_DROME (94-797): 5.65e-82: 285: 16.69		CTNA_DROME (7-891): 0: 930: 51.39
+	Hs
		626280 APC_HUMAN (368-581): 4.56e-43: 173: 23.98		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		626059 APC_HUMAN (368-581): 4.56e-43: 173: 23.98		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		717407 CTNB1_HUMAN (347-576): 1.41e-15: 83.6: 18.41		CTNA3_HUMAN (1-895): 0: 1016: 100.00
+	Hs
		640706 CTNB1_HUMAN (347-576): 1.41e-15: 83.6: 18.41		CTNA2_HUMAN (2-891): 0: 1002: 57.66
+	Hs
		542192 PLAK_HUMAN (347-624): 1.25e-14: 80.5: 16.08		CTNA2_HUMAN (2-891): 0: 1002: 57.66
+	Hs
		716609 CTNB1_HUMAN (347-576): 1.41e-15: 83.6: 18.41		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Hs
		542214 PLAK_HUMAN (347-624): 1.25e-14: 80.5: 16.08		CTNA1_HUMAN (7-891): 0: 992: 59.40
+	Mm
		640689 CTNB1_MOUSE (347-664): 9.56e-16: 84: 16.51		CTNA1_MOUSE (7-891): 0: 986: 59.28
+	Mm
		640690 PLAK_MOUSE (347-624): 8.77e-15: 80.9: 16.08		CTNA1_MOUSE (7-891): 0: 986: 59.28
+	Rn
		1137286 CTNB1_RAT (347-664): 9.72e-16: 84: 16.51		Q5U302_RAT (4-891): 0: 978: 58.95
+	Ce
		218218 HMP2_CAEEL (210-873): 3.71e-71: 251: 13.10		HMP1_CAEEL (9-894): 0: 808: 36.54
+	Ce
		60936 H2L2I2_CAEEL (187-873): 4.69e-72: 254: 13.08		A5JYX3_CAEEL (9-894): 0: 805: 36.43
+	Hs
		575697 CTNB1_HUMAN (347-576): 1.41e-15: 83.6: 18.41		VINC_HUMAN (20-615): 2.01e-62: 231: 15.93