Protein: TRI22
E3 ubiquitin-protein ligase TRIM22 (EC 2.3.2.27) (50 kDa-stimulated trans-acting factor) (RING finger protein 94) (RING-type E3 ubiquitin transferase TRIM22) (Staf-50) (Tripartite motif-containing protein 22)

Gene: TRI22, TRIM22
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q8IYM9

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0002230 - positive regulation of defense response to virus by host
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

668820

PML
Protein PML

2

20

High-throughput

0.754

High

849366

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

Small-scale

0.647

High

1223387

TRI22
E3 ubiquitin-protein ligase TRIM22

1

16

Small-scale

0.647

High

639773

IKBA
NF-kappa-B inhibitor alpha

1

10

Small-scale

0.561

High

1223390

PKHF2
Pleckstrin homology domain-containing family F member 2

2

9

High-throughput

0.553

High

159240

CSKP
Peripheral plasma membrane protein CASK

1

6

High-throughput

0.541

High

556914

CREB1
Cyclic AMP-responsive element-binding protein 1

1

3

High-throughput

0.541

High

1223388

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.541

High

1223389

CIC
Protein capicua homolog

1

4

High-throughput

0.541

High

1223393

RERE
Arginine-glutamic acid dipeptide repeats protein

1

3

High-throughput

0.541

High

1223394

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

4

High-throughput

0.536

High

1074864

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.518

High

1223156

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.518

High

121188

LEG8
Galectin-8

1

13

Small-scale

0.501

High

572401

LEG3
Galectin-3

1

13

Small-scale

0.501

High

167580

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

18

Small-scale

0.479

High

417008

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.479

High

702498

C2TA
MHC class II transactivator

1

14

Small-scale

0.479

High

1019019

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

1223391

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

14

Small-scale

0.479

High

1223392

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

10

Small-scale

0.479

High

1223395

NEMO
NF-kappa-B essential modulator

1

10

Small-scale

0.479

High

1081227

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

Small-scale

0.458

High

1188543

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

776739

STAT3
Signal transducer and activator of transcription 3

1

4

High-throughput

0.445

High


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Last updated: 15 Jul 2024