Interactor 1: SYVN1 (Q86TM6)
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)
Gene: SYVN1

Interactor 2: DERL2 (Q9GZP9)
Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)
Gene: DERL2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 36045259, 16186509, 23867461, 26424800, 19864457, 24366871
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0030970 - retrograde protein transport, ER to cytosol
and 2 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 617
Hs

1 239
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024