HitPredict

Interactor 1: AP3B1 (O00203)
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)
Gene: AP3B1

Interactor 2: CREB3 (O43889)
Cyclic AMP-responsive element-binding protein 3 (CREB-3) (cAMP-responsive element-binding protein 3) (Leucine zipper protein) (Luman) (Transcription factor LZIP-alpha) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3 (N-terminal Luman) (Transcriptionally active form)]
Gene: CREB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0016020 - membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1094 Hs			1 371
+	Hs
		120014 AP3B1_HUMAN (1-1094): 0: 989: 100.00		CR3L1_HUMAN (23-327): 3.61e-45: 164: 27.17
+	Hs
		119976 AP3B1_HUMAN (1-1094): 0: 989: 100.00		CR3L3_HUMAN (26-290): 4.94e-42: 154: 35.32
+	Hs
		1032726 AP3B2_HUMAN (3-1093): 0: 849: 59.69		CR3L3_HUMAN (26-290): 4.94e-42: 154: 35.32