Protein: HAKAI
E3 ubiquitin-protein ligase Hakai (EC 2.3.2.27)

Gene: HAKAI
Organism: Drosophila melanogaster
Interactions: 80
UniProt ID: M9PBE2

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

119838

ARI1
E3 ubiquitin-protein ligase ariadne-1

1

2

High-throughput

0.590

High

119822

HMOC
Homeotic protein ocelliless

1

0

High-throughput

0.473

High

119856

Q9VGW7
type I protein arginine methyltransferase

1

0

High-throughput

0.458

High

119819

ARI2
Potential E3 ubiquitin-protein ligase ariadne-2

1

1

High-throughput

0.457

High

119823

PP2A
Serine/threonine-protein phosphatase PP2A

1

1

High-throughput

0.457

High

119829

Q59E05
Transcription factor Ouib

1

1

High-throughput

0.457

High

119833

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.457

High

119837

Q8T3Y1
CXXC-type zinc finger protein 1

1

1

High-throughput

0.457

High

119873

Q9VSB2
Uncharacterized protein, isoform A

1

1

High-throughput

0.457

High

119884

VIR
Protein virilizer

1

2

High-throughput

0.457

High

56098

APKC
Atypical protein kinase C

1

0

High-throughput

0.438

High

117933

TRIM9
E3 ubiquitin-protein ligase TRIM9

1

0

High-throughput

0.438

High

119821

TERM
Protein terminus

1

0

High-throughput

0.438

High

119824

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.438

High

119825

TTKA
Protein tramtrack, alpha isoform

1

0

High-throughput

0.438

High

119827

EXO1
Exonuclease 1

1

0

High-throughput

0.438

High

119828

RBP9X
Ran-binding proteins 9/10 homolog

1

0

High-throughput

0.438

High

119830

Q7JXC4
CG6459 protein

1

0

High-throughput

0.438

High

119832

IMD
Protein immune deficiency

1

0

High-throughput

0.438

High

119841

Q9V472
DLim1

1

0

High-throughput

0.438

High

119845

Q9V9V8
LP07209p

1

0

High-throughput

0.438

High

119846

Q9VAZ1
AT14585p

1

0

High-throughput

0.438

High

119847

Q9VC48
Methionine aminopeptidase

1

0

High-throughput

0.438

High

119852

Q9VF74
Uncharacterized protein, isoform F

1

0

High-throughput

0.438

High

119857

Q9VHA9
LD25464p

1

0

High-throughput

0.438

High

119858

Q9VHG0
Heterochromatin protein 1e

1

0

High-throughput

0.438

High

119859

Q9VHR4
Uncharacterized protein

1

0

High-throughput

0.438

High

119861

Q9VI24
LD25151p

1

0

High-throughput

0.438

High

119862

UFL1
E3 UFM1-protein ligase 1 homolog

1

0

High-throughput

0.438

High

119864

Q9VJE3
LD24839p

1

0

High-throughput

0.438

High

119866

MSS4
Guanine nucleotide exchange factor MSS4 homolog

1

0

High-throughput

0.438

High

119867

Q9VMD4
FI03607p

1

0

High-throughput

0.438

High

119868

Q9VMS5
Bub1 kinase, isoform A

1

0

High-throughput

0.438

High

119871

SNAPN
SNAPIN protein homolog

1

0

High-throughput

0.438

High

119876

Q9VU18
Uncharacterized protein, isoform C

1

0

High-throughput

0.438

High

119881

Q9VXE7
SD21513p

1

0

High-throughput

0.438

High

119882

Q9VZM9
RE59328p

1

0

High-throughput

0.438

High

119886

ZPR1
Zinc finger protein ZPR1

1

0

High-throughput

0.438

High

119887

Q9W3J9
LP13385p

1

0

High-throughput

0.438

High

119891

XPO2
Exportin-2

1

0

High-throughput

0.438

High

119843

Q9V9R6
No mechanoreceptor potential B, isoform C

1

1

High-throughput

0.417

High

119844

Q9V9V0
Cleavage stimulation factor subunit 1

1

1

High-throughput

0.417

High

119869

Q9VN36
Mucin related 82C

1

2

High-throughput

0.417

High

119875

Q9VSY2
Cleavage and polyadenylation specificity factor subunit 5

1

1

High-throughput

0.417

High

119877

Q9VU72
Uncharacterized protein, isoform A

1

2

High-throughput

0.417

High

119888

Q9W550
FI20216p1

1

1

High-throughput

0.417

High

119892

Q9Y156
BcDNA.GH02976

1

2

High-throughput

0.417

High

54459

A1Z8L7
Uncharacterized protein, isoform C

1

0

High-throughput

0.238

Low

56609

A1ZAC8
Uncharacterized protein, isoform B

1

0

High-throughput

0.238

Low

84553

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.238

Low

119818

O46070
EG:25E8.4 protein

1

0

High-throughput

0.238

Low

119820

O97365
BM-40

1

0

High-throughput

0.238

Low

119826

TSG
Protein twisted gastrulation

1

0

High-throughput

0.238

Low

119831

Q7K127
Alpha-galactosidase

1

0

High-throughput

0.238

Low

119834

Q8IQB8
Tequila, isoform D

1

0

High-throughput

0.238

Low

119835

Q8T0I9
GH27479p

1

0

High-throughput

0.238

Low

119836

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.238

Low

119839

Q9V428
Ras suppressor protein 1

1

0

High-throughput

0.238

Low

119840

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.238

Low

119842

Q9V4B8
RE68558p

1

0

High-throughput

0.238

Low

119848

Q9VCM3
BPTI/Kunitz inhibitor domain-containing protein

1

0

High-throughput

0.238

Low

119849

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.238

Low

119850

Q9VDC1
Deoxyribonuclease TATDN1

1

0

High-throughput

0.238

Low

119851

RPB4
DNA-directed RNA polymerase II subunit Rpb4

1

0

High-throughput

0.238

Low

119853

Q9VFU6
SD04202p

1

0

High-throughput

0.238

Low

119854

Q9VGB9
trypsin

1

0

High-throughput

0.238

Low

119855

Q9VGU7
Arrestin C-terminal-like domain-containing protein

1

0

High-throughput

0.238

Low

119860

Q9VI16
Carnitine O-Acetyl-Transferase, isoform A

1

0

High-throughput

0.238

Low

119863

Q9VJ53
GEO11831p1

1

0

High-throughput

0.238

Low

119865

Q9VKQ0
Uncharacterized protein, isoform A

1

0

High-throughput

0.238

Low

119870

Q9VPE1
Uncharacterized protein, isoform C

1

0

High-throughput

0.238

Low

119872

Q9VRC3
FI09604p

1

0

High-throughput

0.238

Low

119874

Q9VSQ3
GEO07612p1

1

0

High-throughput

0.238

Low

119878

Q9VU89
RE10861p

1

0

High-throughput

0.238

Low

119879

Q9VVV6
LD45843p

1

0

High-throughput

0.238

Low

119880

Q9VXD4
Mab-21-like HhH/H2TH-like domain-containing protein

1

0

High-throughput

0.238

Low

119883

Q9VZT6
CG14957 protein

1

0

High-throughput

0.238

Low

119885

Q9W2M4
Farnesoic acid O-methyl transferase domain-containing protein

1

0

High-throughput

0.238

Low

119889

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.238

Low

119890

Q9W5X1
Asperous, isoform A

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025