HitPredict

Interactor 1: PRP39 (Q86UA1)
Pre-mRNA-processing factor 39 (PRP39 homolog)
Gene: PRPF39

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 780
+	Hs
		1041931 PRP39_HUMAN (1-669): 5.33e-135: 413: 100.00		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1041380 PRP39_HUMAN (1-669): 5.33e-135: 413: 100.00		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		1022276 CSTF3_HUMAN (70-649): 2.04e-61: 219: 16.48		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042591 SYF1_HUMAN (59-663): 8.57e-59: 214: 13.32		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		174869 OGT1_HUMAN (87-568): 1.62e-51: 194: 10.10		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		174870 OGT1_HUMAN (87-568): 1.62e-51: 194: 10.10		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1041587 RRP5_HUMAN (1-281): 1.24e-24: 112: 14.04		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		300133 PRP6_HUMAN (367-666): 9.73e-17: 86.7: 12.09		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		300134 PRP6_HUMAN (367-666): 9.73e-17: 86.7: 12.09		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Sc
		763255 PRP39_YEAST (85-578): 1.78e-62: 221: 16.57		CDC53_YEAST (6-780): 0: 600: 21.43
+	Hs
		1041601 SART3_HUMAN (54-374): 1.33e-09: 63.5: 10.63		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1043357 SART3_HUMAN (54-374): 1.33e-09: 63.5: 10.63		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Dm
		571942 CRN_DROME (42-277): 4.45e-09: 61.6: 12.25		Q8IP45_DROME (5-780): 0: 736: 22.73
+	Dm
		571947 CRN_DROME (42-277): 4.45e-09: 61.6: 12.25		Q9V475_DROME (6-780): 0: 717: 22.64