Protein: MED26
Mediator of RNA polymerase II transcription subunit 26 (Activator-recruited cofactor 70 kDa component) (ARC70) (Cofactor required for Sp1 transcriptional activation subunit 7) (CRSP complex subunit 7) (Mediator complex subunit 26) (Transcriptional coactivator CRSP70)

Gene: MED26
Organism: Homo sapiens
Interactions: 118
UniProt ID: O95402

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

313422

MED21
Mediator of RNA polymerase II transcription subunit 21

7

0

Small-scale

0.922

High

206597

MED7
Mediator of RNA polymerase II transcription subunit 7

7

0

Small-scale

0.921

High

313468

MED4
Mediator of RNA polymerase II transcription subunit 4

7

1

Small-scale

0.752

High

313429

MED1
Mediator of RNA polymerase II transcription subunit 1

6

1

Small-scale

0.738

High

48599

MED19
Mediator of RNA polymerase II transcription subunit 19

10

0

Small-scale

0.722

High

225323

MED14
Mediator of RNA polymerase II transcription subunit 14

5

2

Small-scale

0.718

High

313414

RPB7
DNA-directed RNA polymerase II subunit RPB7

7

0

High-throughput

0.718

High

313403

CDK8
Cyclin-dependent kinase 8

5

1

Small-scale

0.716

High

313462

MED10
Mediator of RNA polymerase II transcription subunit 10

7

0

Small-scale

0.716

High

313463

MED18
Mediator of RNA polymerase II transcription subunit 18

6

0

High-throughput

0.707

High

313465

MED28
Mediator of RNA polymerase II transcription subunit 28

6

0

High-throughput

0.705

High

313470

MED9
Mediator of RNA polymerase II transcription subunit 9

6

0

Small-scale

0.701

High

313469

MED17
Mediator of RNA polymerase II transcription subunit 17

4

1

High-throughput

0.699

High

313452

MED12
Mediator of RNA polymerase II transcription subunit 12

4

1

Small-scale

0.694

High

313459

MED15
Mediator of RNA polymerase II transcription subunit 15

4

1

Small-scale

0.694

High

313475

MED13
Mediator of RNA polymerase II transcription subunit 13

4

1

Small-scale

0.694

High

313471

MED29
Mediator of RNA polymerase II transcription subunit 29

5

0

High-throughput

0.691

High

313464

CDK19
Cyclin-dependent kinase 19

4

1

Small-scale

0.691

High

313480

MED31
Mediator of RNA polymerase II transcription subunit 31

4

0

High-throughput

0.674

High

313409

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

4

0

High-throughput

0.670

High

313440

MED27
Mediator of RNA polymerase II transcription subunit 27

4

0

High-throughput

0.670

High

313466

MED20
Mediator of RNA polymerase II transcription subunit 20

4

0

High-throughput

0.670

High

313472

MED11
Mediator of RNA polymerase II transcription subunit 11

4

0

High-throughput

0.670

High

270464

MED6
Mediator of RNA polymerase II transcription subunit 6

3

1

High-throughput

0.667

High

313399

RPB9
DNA-directed RNA polymerase II subunit RPB9

3

1

High-throughput

0.667

High

313424

MED22
Mediator of RNA polymerase II transcription subunit 22

3

1

High-throughput

0.667

High

313442

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

3

1

High-throughput

0.667

High

313388

RPB3
DNA-directed RNA polymerase II subunit RPB3

4

0

High-throughput

0.664

High

181374

RPB4
DNA-directed RNA polymerase II subunit RPB4

3

0

High-throughput

0.646

High

313389

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

0

High-throughput

0.646

High

313477

MED23
Mediator of RNA polymerase II transcription subunit 23

3

0

High-throughput

0.646

High

265287

MED24
Mediator of RNA polymerase II transcription subunit 24

3

0

High-throughput

0.638

High

313394

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

0

High-throughput

0.638

High

313397

RPB2
DNA-directed RNA polymerase II subunit RPB2

3

0

High-throughput

0.638

High

313408

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

0

High-throughput

0.638

High

313415

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

0

High-throughput

0.638

High

313443

MED25
Mediator of RNA polymerase II transcription subunit 25

3

0

Small-scale

0.638

High

313454

MED8
Mediator of RNA polymerase II transcription subunit 8

3

0

High-throughput

0.638

High

313456

MED30
Mediator of RNA polymerase II transcription subunit 30

3

0

High-throughput

0.638

High

313479

MED16
Mediator of RNA polymerase II transcription subunit 16

3

0

High-throughput

0.638

High

313400

SRBP1
Sterol regulatory element-binding protein 1

3

0

Small-scale

0.613

High

313393

CCNC
Cyclin-C

2

2

High-throughput

0.611

High

313413

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

2

0

High-throughput

0.602

High

130133

ELL2
RNA polymerase II elongation factor ELL2

2

3

High-throughput

0.601

High

313474

AFF4
AF4/FMR2 family member 4

2

1

High-throughput

0.601

High

243747

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

134817

IMA3
Importin subunit alpha-3

2

0

High-throughput

0.576

High

313446

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

0

High-throughput

0.547

High

124148

TAF4
Transcription initiation factor TFIID subunit 4

1

1

High-throughput

0.536

High

236672

CCNT1
Cyclin-T1

1

2

High-throughput

0.536

High

237377

CCNT2
Cyclin-T2

1

2

High-throughput

0.536

High

313391

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.536

High

313402

AF9
Protein AF-9

1

2

High-throughput

0.536

High

313405

CDK9
Cyclin-dependent kinase 9

1

1

High-throughput

0.536

High

313411

ELL
RNA polymerase II elongation factor ELL

1

2

High-throughput

0.536

High

313436

TAF3
Transcription initiation factor TFIID subunit 3

1

1

High-throughput

0.536

High

313444

TAF8
Transcription initiation factor TFIID subunit 8

1

1

High-throughput

0.536

High

313449

TAF4B
Transcription initiation factor TFIID subunit 4B

1

1

High-throughput

0.536

High

313450

RBP56
TATA-binding protein-associated factor 2N

1

1

High-throughput

0.536

High

313453

EAF2
ELL-associated factor 2

1

1

High-throughput

0.536

High

313457

EAF1
ELL-associated factor 1

1

1

High-throughput

0.536

High

313390

TBP
TATA-box-binding protein

1

0

High-throughput

0.513

High

313404

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.513

High

313410

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.513

High

313420

TAF10
Transcription initiation factor TFIID subunit 10

1

0

High-throughput

0.513

High

313425

TAF5
Transcription initiation factor TFIID subunit 5

1

0

High-throughput

0.513

High

313426

TAF13
Transcription initiation factor TFIID subunit 13

1

0

High-throughput

0.513

High

313427

TAF11
Transcription initiation factor TFIID subunit 11

1

0

High-throughput

0.513

High

313428

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.513

High

313431

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.513

High

313437

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.513

High

313439

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.513

High

313455

GWL
Serine/threonine-protein kinase greatwall

1

0

High-throughput

0.513

High

313478

ICE1
Little elongation complex subunit 1

1

0

High-throughput

0.513

High

313406

AFF1
AF4/FMR2 family member 1

1

1

High-throughput

0.489

High

160304

AURKA
Aurora kinase A

1

0

Small-scale

0.480

High

313482

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

Small-scale

0.480

High

266292

TAD2A
Transcriptional adapter 2-alpha

1

1

High-throughput

0.479

High

313392

TCEA1
Transcription elongation factor A protein 1

1

1

High-throughput

0.479

High

313395

BRD2
Bromodomain-containing protein 2

1

3

High-throughput

0.479

High

313418

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

313419

ENL
Protein ENL

1

1

High-throughput

0.479

High

313423

ELOA1
Elongin-A

1

1

High-throughput

0.479

High

313445

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

1

High-throughput

0.479

High

313458

QKI
KH domain-containing RNA-binding protein QKI

1

1

High-throughput

0.479

High

246521

MCE1
mRNA-capping enzyme

1

0

High-throughput

0.458

High

304566

SCAF4
SR-related and CTD-associated factor 4

1

0

High-throughput

0.458

High

313387

CEBPB
CCAAT/enhancer-binding protein beta

1

0

Small-scale

0.458

High

313396

PML
Protein PML

1

0

High-throughput

0.458

High

313417

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

313421

SMAD4
Mothers against decapentaplegic homolog 4

1

0

Small-scale

0.458

High

313434

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

0

High-throughput

0.458

High

313435

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

0

High-throughput

0.458

High

313441

ACD11
Acyl-CoA dehydrogenase family member 11

1

0

High-throughput

0.458

High

313451

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.458

High

313460

EPAS1
Endothelial PAS domain-containing protein 1

1

0

Small-scale

0.458

High

313467

ELL3
RNA polymerase II elongation factor ELL3

1

2

High-throughput

0.445

High

295479

RECQ5
ATP-dependent DNA helicase Q5

1

0

High-throughput

0.426

High

303987

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.426

High

313384

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.426

High

313398

HS71L
Heat shock 70 kDa protein 1-like

1

0

High-throughput

0.426

High

313401

LAP2A
Lamina-associated polypeptide 2, isoform alpha

1

0

High-throughput

0.426

High

313407

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

0

High-throughput

0.426

High

313432

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

313433

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.426

High

313448

TITIN
Titin

1

0

High-throughput

0.426

High

313473

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.426

High

313481

TRRAP
Transformation/transcription domain-associated protein

1

0

Small-scale

0.426

High

313430

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.279

Low

313447

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

313438

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.249

Low

313385

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.232

Low

313386

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

0

High-throughput

0.232

Low

313412

IF4A1
Eukaryotic initiation factor 4A-I

1

0

High-throughput

0.232

Low

313416

DCD
Dermcidin

1

0

High-throughput

0.232

Low

313461

DDX50
ATP-dependent RNA helicase DDX50

1

0

High-throughput

0.232

Low

313476

GPN3
GPN-loop GTPase 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024