HitPredict

Interactor 1: AP3B1 (O00203)
AP-3 complex subunit beta-1 (Adaptor protein complex AP-3 subunit beta-1) (Adaptor-related protein complex 3 subunit beta-1) (Beta-3A-adaptin) (Clathrin assembly protein complex 3 beta-1 large chain)
Gene: AP3B1

Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1094 Hs			1 418
+	Hs
		119923 AP3B1_HUMAN (1-1094): 0: 989: 100.00		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		685933 AP3B2_HUMAN (3-1093): 0: 849: 59.69		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		827157 AP2B1_HUMAN (33-744): 0: 558: 25.14		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		321510 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		ARRB1_HUMAN (1-418): 0: 716: 100.00
+	Hs
		685891 AP2B1_HUMAN (33-744): 0: 558: 25.14		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Rn
		663951 AP2B1_RAT (33-744): 0: 558: 25.14		ARRB2_RAT (1-407): 0: 616: 75.00
+	Hs
		685925 AP1B1_HUMAN (33-725): 2.94e-176: 542: 25.56		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		321494 AP2A1_HUMAN (42-648): 1.93e-154: 486: 14.02		ARRB2_HUMAN (1-407): 0: 626: 76.15
+	Hs
		302104 AP2A2_HUMAN (42-660): 3.11e-152: 479: 12.87		ARRB2_HUMAN (1-407): 0: 626: 76.15