Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.901

The method score is based on:

Property Details
Experiments 22139835, 22474354, 23155421, 31319868, 23059983
Identification Methods mammalian protein protein interaction trap, anti tag coimmunoprecipitation, tox-r dimerization assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_4~LRR_4, LRR_4~LRR_6, LRR_4~LRR_8, LRR_6~LRR_6, LRR_6~LRR_8, LRR_8~LRR_8, TIR~TIR
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0001540 - amyloid-beta binding
GO:0001726 - ruffle
GO:0001875 - lipopolysaccharide immune receptor activity
GO:0001891 - phagocytic cup
and 100 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 839
Hs

1 839
+ Mm
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+ At
+ At
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024