Protein: MED19
Mediator of RNA polymerase II transcription subunit 19 (Mediator complex subunit 19)

Gene: MED19
Organism: Drosophila melanogaster
Interactions: 76
UniProt ID: Q9VVL6

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0140297 - DNA-binding transcription factor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1378944

Q960F7
SD03629p

3

1

High-throughput

0.585

High

1428001

MED10
Mediator of RNA polymerase II transcription subunit 10

1

1

High-throughput

0.575

High

1428110

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

High-throughput

0.575

High

1487354

MED14
Mediator of RNA polymerase II transcription subunit 14

1

1

High-throughput

0.575

High

1483014

MED1
Mediator of RNA polymerase II transcription subunit 1

2

1

Small-scale

0.571

High

1014409

UBX
Homeotic protein ultrabithorax

2

4

Small-scale

0.566

High

458237

DFD
Homeotic protein deformed

1

5

Small-scale

0.552

High

713733

ABDA
Homeobox protein abdominal-A

1

6

Small-scale

0.552

High

1172859

DEAF1
Deformed epidermal autoregulatory factor 1

1

1

High-throughput

0.552

High

1445129

Q9N693
Brakeless-B

1

0

Small-scale

0.529

High

1321938

Q8MYX3
RE59988p

1

1

High-throughput

0.494

High

1458110

Q9U8L5
Dorsocross1, isoform A

1

1

High-throughput

0.481

High

393651

ANTP
Homeotic protein antennapedia

1

4

Small-scale

0.479

High

478774

SCR
Homeotic protein Sex combs reduced

1

5

Small-scale

0.479

High

478962

ABDB
Homeobox protein abdominal-B

1

5

Small-scale

0.479

High

518543

LAB
Homeotic protein labial

1

4

Small-scale

0.479

High

724953

HMPB
Homeotic protein proboscipedia

1

3

Small-scale

0.479

High

385021

HSP27
Heat shock protein 27

1

2

High-throughput

0.464

High

1486167

R10AB
Large ribosomal subunit protein uL1

1

1

High-throughput

0.464

High

1192919

YAP1
Transcriptional coactivator yorkie

1

0

Small-scale

0.458

High

2360

A0A0B4KEQ7
Regulatory protein zeste

1

1

High-throughput

0.451

High

1070359

Q0IGU0
IP21556p

1

1

High-throughput

0.451

High

1285959

Q86LC7
Deformed epidermal autoregulatory factor-1, isoform B

1

1

High-throughput

0.451

High

58513

MED8
Mediator of RNA polymerase II transcription subunit 8

1

2

High-throughput

0.445

High

1269636

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.445

High

1302898

MED31
Mediator of RNA polymerase II transcription subunit 31

1

2

High-throughput

0.445

High

1377803

EBI
F-box-like/WD repeat-containing protein ebi

1

1

High-throughput

0.445

High

1471840

MED25
Mediator of RNA polymerase II transcription subunit 25

1

1

High-throughput

0.445

High

1472614

MED17
Mediator of RNA polymerase II transcription subunit 17

1

1

High-throughput

0.445

High

1482741

MED27
Mediator of RNA polymerase II transcription subunit 27

1

1

High-throughput

0.445

High

1485341

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.445

High

1485573

MED24
Mediator of RNA polymerase II transcription subunit 24

1

1

High-throughput

0.445

High

1485960

CDK8
Cyclin-dependent kinase 8

1

3

High-throughput

0.445

High

1487348

MED11
Mediator of RNA polymerase II transcription subunit 11

1

1

High-throughput

0.445

High

1487350

MED12
Mediator of RNA polymerase II transcription subunit 12

1

2

High-throughput

0.445

High

1487352

BAP60
Brahma-associated protein of 60 kDa

1

1

High-throughput

0.445

High

1487353

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

High-throughput

0.445

High

1487355

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.445

High

1487356

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

High-throughput

0.445

High

84691

B7Z0C5
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

120109

M9PCD4
Liprin-alpha, isoform E

1

1

High-throughput

0.439

High

1266101

Q7K3Q3
Regulatory protein zeste

1

1

High-throughput

0.439

High

1487357

X2JCR2
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

197489

O18353
CHIP

1

0

High-throughput

0.426

High

1472588

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

1

0

High-throughput

0.426

High

1069262

Q0E8G5
Uncharacterized protein, isoform D

1

1

High-throughput

0.417

High

1481605

Q9VM93
LD33094p

1

1

High-throughput

0.417

High

1485314

Q9VS26
GEO11440p1

1

1

High-throughput

0.417

High

1409400

Q9BIW6
Brahma-associated protein 111kD

1

1

High-throughput

0.407

High

1344685

Q8SYU5
RE33762p

3

0

High-throughput

0.340

High

56047

A1Z9S3
FI16815p1

2

0

High-throughput

0.310

High

1374869

DYLT
Dynein light chain Tctex-type

2

0

High-throughput

0.310

High

1469877

Q9VC28
60S ribosome subunit biogenesis protein NIP7 homolog

2

0

High-throughput

0.310

High

263460

O61351
La costa

1

0

High-throughput

0.265

Low

614775

TY3H
Tyrosine 3-monooxygenase

1

0

High-throughput

0.265

Low

631764

GNAI
G protein alpha i subunit

1

0

High-throughput

0.265

Low

929243

OAZ
Ornithine decarboxylase antizyme

1

0

High-throughput

0.265

Low

1010244

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.265

Low

1064254

SQD
RNA-binding protein squid

1

0

High-throughput

0.265

Low

1463570

Q9V3G9
AT18705p

1

0

High-throughput

0.265

Low

1473574

B9D1
B9 domain-containing protein 1

1

0

High-throughput

0.265

Low

1479202

Q9VK57
PIH1 domain-containing protein 1

1

0

High-throughput

0.265

Low

1481240

Q9VLT7
IP17351p

1

0

High-throughput

0.265

Low

1484589

Q9VR26
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1485244

Q9VRX7
LD29573p

1

0

High-throughput

0.265

Low

1485770

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.265

Low

1487349

Q9VW41
Protein MIX23

1

0

High-throughput

0.265

Low

1487351

Q9VW52
Precursor RNA processing 3, isoform A

1

0

High-throughput

0.265

Low

55744

A1Z9J6
Large ribosomal subunit protein mL53

1

0

High-throughput

0.238

Low

84729

UNR
RNA-binding protein Unr

1

0

High-throughput

0.232

Low

900678

DSH
Segment polarity protein dishevelled

1

0

High-throughput

0.232

Low

1346033

ENA
Protein enabled

1

0

High-throughput

0.232

Low

1346446

MESD
LDLR chaperone boca

1

0

High-throughput

0.232

Low

1480271

Q9VL29
GEO11246p1

1

0

High-throughput

0.232

Low

1485608

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.232

Low

1486600

Q9VUB7
PAX-interacting protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025