Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4
Interactor 2: CD14 (P08571)
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form]
Gene: CD14
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12196527 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_4~LRR_6, LRR_6~LRR_6, LRR_6~LRR_8 |
| Common GO terms | GO:0001530 - lipopolysaccharide binding GO:0001875 - lipopolysaccharide immune receptor activity GO:0005886 - plasma membrane GO:0006909 - phagocytosis GO:0006954 - inflammatory response and 10 others more... |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
