HitPredict

Interactor 1: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Interactor 2: DYRK2 (Q92630)
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
Gene: DYRK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 953 Hs			1 601
+	Hs
		414977 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CDK1_HUMAN (219-538): 9.81e-126: 373: 27.13
+	Hs
		1268608 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		DYRK2_HUMAN (1-601): 0: 534: 100.00
+	Hs
		1264773 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		DYRK2_HUMAN (1-601): 0: 534: 100.00
+	Hs
		625642 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		833765 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		1044321 PCLO_HUMAN (54-952): 1.43e-31: 136: 7.21		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Hs
		1201686 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CLK4_HUMAN (204-535): 1.85e-59: 207: 33.71
+	Hs
		625528 TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54		CDK2_HUMAN (219-543): 6.32e-142: 415: 27.71
+	Hs
		833914 ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		1043978 THOC2_HUMAN (248-635): 6.8e-20: 98.2: 14.15		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Dm
		820723 CPN_DROME (301-945): 3.37e-18: 92.1: 8.23		CDK5_DROME (219-537): 9.18e-117: 350: 25.08
+	Hs
		152642 KMT2D_HUMAN (379-947): 6.05e-11: 69: 11.30		DYR1A_HUMAN (211-537): 2.66e-117: 367: 42.52
+	Mm
		581220 NFH_MOUSE (581-953): 7.33e-14: 78.2: 13.41		CDK5_MOUSE (219-541): 4.27e-119: 356: 28.10
+	Hs
		833803 MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		833836 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		1335031 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK4_HUMAN (204-535): 1.85e-59: 207: 33.71
+	Hs
		833769 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		CLK1_HUMAN (204-535): 3.1e-62: 215: 35.80
+	Hs
		833993 SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		833918 SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56
+	Hs
		3286 A0A0S2Z4Z6_HUMAN (97-903): 3.62e-14: 79: 10.66		CLK2_HUMAN (204-543): 6.41e-57: 201: 31.56