HitPredict

Interactor 1: TLR4 (O00206)
Toll-like receptor 4 (hToll) (CD antigen CD284)
Gene: TLR4

Interactor 2: TLR6 (Q9Y2C9)
Toll-like receptor 6 (CD antigen CD286)
Gene: TLR6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 20037584
Identification Methods anti tag coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_4~LRR_8, LRR_6~LRR_8, LRR_8~LRR_8, LRR_8~LRRCT, TIR~TIR
Common GO terms GO:0001540 - amyloid-beta binding
GO:0002224 - toll-like receptor signaling pathway
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005102 - signaling receptor binding
and 22 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 839
Hs

1 796
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024