HitPredict

Interactor 1: RASF3 (Q86WH2)
Ras association domain-containing protein 3
Gene: RASSF3

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	20920251
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 238 Hs			1 383
+	Hs
		1330813 RASF1_HUMAN (33-231): 3.83e-93: 278: 44.84		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		1262936 RASF5_HUMAN (25-233): 1.3e-90: 274: 45.06		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		841565 RASF2_HUMAN (106-234): 1.62e-46: 158: 29.20		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		1336090 RASF1_HUMAN (33-231): 3.83e-93: 278: 44.84		SMUF1_HUMAN (147-381): 2.43e-59: 206: 18.32
+	Hs
		1172536 RASF6_HUMAN (106-232): 9.11e-42: 147: 22.39		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		1329566 RASF4_HUMAN (106-234): 5.97e-33: 123: 29.20		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		1294869 RASF1_HUMAN (33-231): 3.83e-93: 278: 44.84		ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36
+	Hs
		1262928 RASF5_HUMAN (25-233): 1.3e-90: 274: 45.06		ITCH_HUMAN (41-315): 8.61e-36: 141: 19.36
+	Dm
		1363056 Q9VCQ7_DROME (5-234): 1.53e-43: 157: 19.18		SAV_DROME (81-373): 5.46e-33: 131: 32.12