HitPredict

Interactor 1: DDX42 (Q86XP3)
ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125)
Gene: DDX42

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31950832
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 938 Hs			1 334
+	Hs
		1271613 DDX17_HUMAN (189-774): 3.85e-154: 473: 34.33		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		571540 DDX5_HUMAN (197-734): 2.1e-147: 452: 35.37		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		134148 DDX3X_HUMAN (123-662): 1.87e-134: 420: 29.84		CSN5_HUMAN (1-334): 6.64e-131: 378: 100.00
+	Hs
		131026 DDX17_HUMAN (189-774): 3.85e-154: 473: 34.33		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		130730 DDX5_HUMAN (197-734): 2.1e-147: 452: 35.37		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Sc
		624119 DBP2_YEAST (152-635): 2.59e-141: 433: 37.86		RPN11_YEAST (39-333): 9.57e-75: 234: 29.14
+	Hs
		124753 DDX5_HUMAN (197-734): 2.1e-147: 452: 35.37		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		133773 DDX3X_HUMAN (123-662): 1.87e-134: 420: 29.84		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57
+	Hs
		124663 DDX3X_HUMAN (123-662): 1.87e-134: 420: 29.84		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		124677 DDX3Y_HUMAN (83-662): 2.89e-133: 416: 29.07		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48