Protein: MO4L2
Mortality factor 4-like protein 2 (MORF-related gene X protein) (Protein MSL3-2) (Transcription factor-like protein MRGX)

Gene: MO4L2, MORF4L2
Organism: Homo sapiens
Interactions: 207
UniProt ID: Q15014

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005886 - plasma membrane
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1136842

PHF12
PHD finger protein 12

9

6

Small-scale

0.969

High

1136875

MO4L1
Mortality factor 4-like protein 1

8

4

Small-scale

0.966

High

274331

SIN3B
Paired amphipathic helix protein Sin3b

5

5

Small-scale

0.902

High

711819

KDM5A
Lysine-specific demethylase 5A

4

5

Small-scale

0.881

High

1136894

MOFA1
MORF4 family-associated protein 1

12

3

Small-scale

0.760

High

1136866

MRGBP
MRG/MORF4L-binding protein

13

2

Small-scale

0.760

High

1136810

PALB2
Partner and localizer of BRCA2

8

1

Small-scale

0.750

High

1136854

BRD8
Bromodomain-containing protein 8

8

2

Small-scale

0.746

High

1053290

MBTD1
MBT domain-containing protein 1

7

3

Small-scale

0.745

High

1136829

KAT5
Histone acetyltransferase KAT5

7

10

Small-scale

0.745

High

1136856

EPC1
Enhancer of polycomb homolog 1

7

5

Small-scale

0.745

High

1136892

TRRAP
Transformation/transcription domain-associated protein

6

3

Small-scale

0.732

High

1136787

EPC2
Enhancer of polycomb homolog 2

6

5

Small-scale

0.729

High

1136840

EP400
E1A-binding protein p400

6

5

Small-scale

0.729

High

340327

YETS4
YEATS domain-containing protein 4

5

2

Small-scale

0.712

High

1136862

DMAP1
DNA methyltransferase 1-associated protein 1

5

4

Small-scale

0.712

High

1136863

ASH1L
Histone-lysine N-methyltransferase ASH1L

5

5

Small-scale

0.712

High

1136777

VPS72
Vacuolar protein sorting-associated protein 72 homolog

5

1

Small-scale

0.709

High

833736

KDM5C
Lysine-specific demethylase 5C

1

5

High-throughput

0.691

High

1136860

EAF6
Chromatin modification-related protein MEAF6

4

1

Small-scale

0.691

High

1136870

ING3
Inhibitor of growth protein 3

4

3

Small-scale

0.691

High

1136887

RUVB2
RuvB-like 2

4

4

Small-scale

0.686

High

1136888

RUVB1
RuvB-like 1

4

4

Small-scale

0.686

High

1136839

LMBL3
Lethal(3)malignant brain tumor-like protein 3

3

4

High-throughput

0.675

High

1136806

EMSY
BRCA2-interacting transcriptional repressor EMSY

4

4

Small-scale

0.672

High

1136823

GATD1
GATA zinc finger domain-containing protein 1

4

1

High-throughput

0.672

High

904290

BRCA2
Breast cancer type 2 susceptibility protein

3

3

Small-scale

0.667

High

1136837

MR1L1
MORF4 family-associated protein 1-like 1

5

3

High-throughput

0.662

High

1109736

HDAC1
Histone deacetylase 1

3

6

Small-scale

0.640

High

1136779

RBBP7
Histone-binding protein RBBP7

3

2

Small-scale

0.640

High

1136782

H2B2E
Histone H2B type 2-E

3

9

Small-scale

0.640

High

1136827

HDAC2
Histone deacetylase 2

3

6

Small-scale

0.640

High

1136769

TNIP1
TNFAIP3-interacting protein 1

2

2

High-throughput

0.628

High

1136768

MO4L2
Mortality factor 4-like protein 2

1

4

Small-scale

0.618

High

1136828

KAT6A
Histone acetyltransferase KAT6A

1

10

High-throughput

0.618

High

1136843

SIN3A
Paired amphipathic helix protein Sin3a

1

5

Small-scale

0.618

High

1136832

DDT4L
DNA damage-inducible transcript 4-like protein

3

1

High-throughput

0.616

High

1136831

H2B1A
Histone H2B type 1-A

2

8

High-throughput

0.611

High

914612

RM12
Large ribosomal subunit protein bL12m

2

1

High-throughput

0.606

High

1048857

REL
Proto-oncogene c-Rel

2

2

High-throughput

0.606

High

1110245

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

1

High-throughput

0.606

High

1136775

NAB2
NGFI-A-binding protein 2

2

1

High-throughput

0.606

High

1136796

HMBX1
Homeobox-containing protein 1

2

1

High-throughput

0.606

High

1136801

KCTD1
BTB/POZ domain-containing protein KCTD1

2

1

High-throughput

0.606

High

1136824

TRI41
E3 ubiquitin-protein ligase TRIM41

2

1

High-throughput

0.606

High

1136845

ARI3A
AT-rich interactive domain-containing protein 3A

2

7

High-throughput

0.606

High

1136861

ZBT26
Zinc finger and BTB domain-containing protein 26

2

6

High-throughput

0.606

High

1136864

PICK1
PRKCA-binding protein

2

2

High-throughput

0.606

High

1136885

SATB2
DNA-binding protein SATB2

2

0

High-throughput

0.602

High

501992

H2AZ
Histone H2A.Z

2

6

Small-scale

0.601

High

355215

ACL6A
Actin-like protein 6A

2

8

Small-scale

0.584

High

372062

MYC
Myc proto-oncogene protein

2

5

High-throughput

0.584

High

952828

ACTB
Actin, cytoplasmic 1

2

6

Small-scale

0.584

High

1136773

TSN
Translin

2

0

High-throughput

0.580

High

1136808

GPBP1
Vasculin

2

0

High-throughput

0.580

High

1136855

BC11A
BCL11 transcription factor A

2

0

High-throughput

0.580

High

1136889

AMOL2
Angiomotin-like protein 2

2

0

High-throughput

0.580

High

355525

NSD2
Histone-lysine N-methyltransferase NSD2

1

5

High-throughput

0.575

High

1136844

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

3

High-throughput

0.575

High

212842

ZBT43
Zinc finger and BTB domain-containing protein 43

2

9

High-throughput

0.573

High

180151

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

3

High-throughput

0.573

High

1104580

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.573

High

1136814

PHC2
Polyhomeotic-like protein 2

1

2

High-throughput

0.573

High

1136817

FAM9B
Protein FAM9B

1

1

High-throughput

0.573

High

1136834

ZBT10
Zinc finger and BTB domain-containing protein 10

1

5

High-throughput

0.573

High

1136848

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.573

High

1136867

THAP1
THAP domain-containing protein 1

1

1

High-throughput

0.573

High

396133

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

1136780

IF16
Gamma-interferon-inducible protein 16

2

1

High-throughput

0.571

High

1136776

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

2

1

High-throughput

0.567

High

1136790

BEX5
Protein BEX5

2

1

High-throughput

0.553

High

1136813

FBX16
F-box only protein 16

2

3

High-throughput

0.553

High

229331

ZBT14
Zinc finger and BTB domain-containing protein 14

1

0

High-throughput

0.549

High

1136881

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.549

High

1136807

JAZF1
Juxtaposed with another zinc finger protein 1

1

1

High-throughput

0.536

High

1136800

E400N
Putative EP400-like protein

2

3

High-throughput

0.533

High

442719

RB
Retinoblastoma-associated protein

1

2

Small-scale

0.527

High

852123

TNNT2
Troponin T, cardiac muscle

1

2

High-throughput

0.523

High

1061699

TLE5
TLE family member 5

1

1

High-throughput

0.523

High

1063258

GOGA2
Golgin subfamily A member 2

1

3

High-throughput

0.523

High

1136819

BEND7
BEN domain-containing protein 7

1

1

High-throughput

0.523

High

249137

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.518

High

608271

EGLN
Endoglin

1

0

High-throughput

0.513

High

1085554

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.513

High

1136891

EXOS1
Exosome complex component CSL4

1

0

High-throughput

0.513

High

843571

HD
Huntingtin

1

0

High-throughput

0.493

High

1136797

FOXR1
Forkhead box protein R1

1

3

High-throughput

0.489

High

1136812

HOMEZ
Homeobox and leucine zipper protein Homez

1

1

High-throughput

0.481

High

259967

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

315596

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

385755

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

Small-scale

0.479

High

406193

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

588727

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

695489

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

768224

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

799128

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

904728

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

910520

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

Small-scale

0.479

High

910907

IMA1
Importin subunit alpha-1

1

2

Small-scale

0.479

High

913774

ZN131
Zinc finger protein 131

1

2

Small-scale

0.479

High

959584

MAX
Protein max

1

5

Small-scale

0.479

High

965681

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

Small-scale

0.479

High

979680

H4
Histone H4

1

4

High-throughput

0.479

High

980778

H2B1C
Histone H2B type 1-C/E/F/G/I

1

9

High-throughput

0.479

High

993179

ACTG
Actin, cytoplasmic 2

1

6

Small-scale

0.479

High

998330

H31
Histone H3.1

1

10

High-throughput

0.479

High

1004582

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

1016871

H33
Histone H3.3

1

10

High-throughput

0.479

High

1027469

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

2

Small-scale

0.479

High

1107730

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1128722

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

1134199

IMB1
Importin subunit beta-1

1

1

Small-scale

0.479

High

1136770

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

1136778

EZH2
Histone-lysine N-methyltransferase EZH2

1

5

High-throughput

0.479

High

1136781

H2A2C
Histone H2A type 2-C

1

2

Small-scale

0.479

High

1136792

HABP4
Intracellular hyaluronan-binding protein 4

1

1

High-throughput

0.479

High

1136798

FOXR2
Forkhead box protein R2

1

3

High-throughput

0.479

High

1136799

SRCAP
Helicase SRCAP

1

3

Small-scale

0.479

High

1136802

TBA1A
Tubulin alpha-1A chain

1

3

Small-scale

0.479

High

1136803

H2AV
Histone H2A.V

1

6

Small-scale

0.479

High

1136820

FNDC5
Fibronectin type III domain-containing protein 5

1

1

Small-scale

0.479

High

1136833

MBD6
Methyl-CpG-binding domain protein 6

1

3

High-throughput

0.479

High

1136876

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1136880

HDAC9
Histone deacetylase 9

1

7

Small-scale

0.479

High

1136884

FZR1
Fizzy-related protein homolog

1

2

High-throughput

0.479

High

1136783

Q17R54
Synapsin III

1

4

High-throughput

0.470

High

1136786

Q4G0R1
PIBF1 protein

1

4

High-throughput

0.470

High

1136795

Q6FHY5
MEOX2 protein

1

4

High-throughput

0.470

High

1136818

Q8N4I8
KLHL3 protein

1

1

High-throughput

0.470

High

320681

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

324873

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

766565

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

791390

SYUA
Alpha-synuclein

1

0

Small-scale

0.458

High

1092130

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1105926

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

0

High-throughput

0.458

High

1136830

FBXW7
F-box/WD repeat-containing protein 7

1

0

Small-scale

0.458

High

1136853

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1136893

MAFB
Transcription factor MafB

1

0

High-throughput

0.458

High

529817

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

697121

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

Small-scale

0.445

High

926358

BLM
RecQ-like DNA helicase BLM

1

2

High-throughput

0.445

High

937254

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

1

High-throughput

0.445

High

1110986

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.445

High

1136771

TTF1
Transcription termination factor 1

1

1

High-throughput

0.445

High

1136774

TRBP2
RISC-loading complex subunit TARBP2

1

1

High-throughput

0.445

High

1136785

GLYR1
Cytokine-like nuclear factor N-PAC

1

1

High-throughput

0.445

High

1136822

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.445

High

1136825

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

1

High-throughput

0.445

High

1136847

BUD13
BUD13 homolog

1

1

High-throughput

0.445

High

1136850

AN32E
Acidic leucine-rich nuclear phosphoprotein 32 family member E

1

1

Small-scale

0.445

High

1136852

GTPB4
GTP-binding protein 4

1

2

High-throughput

0.445

High

1136859

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

1

High-throughput

0.445

High

1136874

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.445

High

174190

SYN3
Synapsin-3

1

3

High-throughput

0.439

High

893870

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.439

High

1136826

PIBF1
Progesterone-induced-blocking factor 1

1

4

High-throughput

0.439

High

1136878

KLHL3
Kelch-like protein 3

1

1

High-throughput

0.439

High

1136838

SPTCS
Spatacsin

1

0

Small-scale

0.438

High

761684

HSP74
Heat shock 70 kDa protein 4

1

2

Small-scale

0.437

High

893445

RET2
Retinol-binding protein 2

1

1

Small-scale

0.437

High

996455

ACTS
Actin, alpha skeletal muscle

1

5

Small-scale

0.437

High

1118475

TBB2A
Tubulin beta-2A chain

1

1

Small-scale

0.437

High

1136821

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.437

High

61937

GTPBA
GTP-binding protein 10

1

0

High-throughput

0.426

High

244362

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.426

High

1136772

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.426

High

1136784

KNOP1
Lysine-rich nucleolar protein 1

1

0

High-throughput

0.426

High

1136789

ESCO2
N-acetyltransferase ESCO2

1

0

High-throughput

0.426

High

1136794

SPT2
Protein SPT2 homolog

1

0

High-throughput

0.426

High

1136804

NOL8
Nucleolar protein 8

1

0

High-throughput

0.426

High

1136811

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.426

High

1136816

DHX37
Probable ATP-dependent RNA helicase DHX37

1

0

High-throughput

0.426

High

1136835

PRR11
Proline-rich protein 11

1

0

High-throughput

0.426

High

1136846

SEM3C
Semaphorin-3C

1

0

High-throughput

0.426

High

1136849

TRI56
E3 ubiquitin-protein ligase TRIM56

1

0

High-throughput

0.426

High

1136851

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.426

High

1136858

DDX31
ATP-dependent DNA helicase DDX31

1

0

High-throughput

0.426

High

1136868

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.426

High

1136869

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.426

High

1136871

TAP26
Thyroid transcription factor 1-associated protein 26

1

0

High-throughput

0.426

High

1136877

PARP2
Poly [ADP-ribose] polymerase 2

1

0

High-throughput

0.426

High

1136883

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.426

High

1136890

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.426

High

1136788

CEP55
Centrosomal protein of 55 kDa

3

0

High-throughput

0.352

High

1136865

DISC1
Disrupted in schizophrenia 1 protein

3

0

High-throughput

0.339

High

1136841

ZNF48
Zinc finger protein 48

3

0

High-throughput

0.337

High

248984

EVI5
Ecotropic viral integration site 5 protein homolog

2

0

High-throughput

0.316

High

1007923

PO6F2
POU domain, class 6, transcription factor 2

2

0

High-throughput

0.316

High

1136872

LUZP4
Leucine zipper protein 4

2

0

High-throughput

0.316

High

1033355

CDR2
Cerebellar degeneration-related protein 2

1

0

Small-scale

0.305

High

1136836

GRM2B
GRAM domain-containing protein 2B

1

0

High-throughput

0.299

High

943578

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.282

High

1136879

ITBP2
Integrin beta-1-binding protein 2

1

0

High-throughput

0.279

Low

276959

MPU1
Mannose-P-dolichol utilization defect 1 protein

1

0

High-throughput

0.269

Low

1024277

PIPNA
Phosphatidylinositol transfer protein alpha isoform

1

0

High-throughput

0.269

Low

157392

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

1095639

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

0

High-throughput

0.249

Low

1136793

RC3H1
Roquin-1

1

0

High-throughput

0.249

Low

1136873

Q9P156
HCG2022592

1

0

High-throughput

0.249

Low

1136882

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1136791

DDX6L
Probable ATP-dependent RNA helicase DDX60-like

1

0

High-throughput

0.232

Low

1136805

CLAP1
CLIP-associating protein 1

1

0

High-throughput

0.232

Low

1136809

SPAS2
Spermatogenesis-associated serine-rich protein 2

1

0

High-throughput

0.232

Low

1136815

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

0

High-throughput

0.232

Low

1136857

CH033
UPF0488 protein C8orf33

1

0

High-throughput

0.232

Low

1136886

DICER
Endoribonuclease Dicer

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025