HitPredict

Interactor 1: GOLI (Q86XS8)
E3 ubiquitin-protein ligase RNF130 (EC 2.3.2.27) (Goliath homolog) (H-Goliath) (RING finger protein 130) (RING-type E3 ubiquitin transferase RNF130)
Gene: RNF130

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36610398
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005737 - cytoplasm GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 419 Hs			1 589
+	Hs
		1204861 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		1204844 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Hs
		1240835 RN149_HUMAN (25-343): 1.03e-80: 255: 41.85		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Hs
		1255992 RN128_HUMAN (1-384): 4.57e-89: 278: 36.90		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		924340 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		924057 GOLI_HUMAN (1-419): 4.48e-123: 365: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		803648 RN149_HUMAN (25-343): 1.03e-80: 255: 41.85		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Hs
		803617 SYVN1_HUMAN (17-312): 1.08e-56: 198: 14.38		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Hs
		924365 ZNRF4_HUMAN (6-375): 3.81e-59: 200: 18.95		RL40_HUMAN (37-126): 1.88e-34: 128: 30.77
+	Hs
		803801 AMFR_HUMAN (2-346): 7.99e-45: 166: 13.50		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Hs
		924212 AMFR_HUMAN (2-346): 7.99e-45: 166: 13.50		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		803773 RNF12_HUMAN (210-311): 1.31e-10: 65.1: 33.33		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66
+	Hs
		803824 RN115_HUMAN (237-305): 5.8e-11: 65.1: 44.93		BAG6_HUMAN (25-536): 2.14e-33: 138: 14.66