HitPredict

Interactor 1: MIB1 (Q86YT6)
E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2)
Gene: MIB1

Interactor 2: MIB2 (Q96AX9)
E3 ubiquitin-protein ligase MIB2 (EC 2.3.2.27) (Mind bomb homolog 2) (Novel zinc finger protein) (Novelzin) (Putative NF-kappa-B-activating protein 002N) (RING-type E3 ubiquitin transferase MIB2) (Skeletrophin) (Zinc finger ZZ type with ankyrin repeat domain protein 1)
Gene: MIB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 21903422
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank_2, Ank_2~Ank_2, Ank~Ank_4, Ank_2~Ank_4, MIB_HERC2~MIB_HERC2, MIB_HERC2~SH3_15, SH3_15~SH3_15, SH3_15~ZZ, zf-C3HC4_3~zf-C3HC4_3, ZZ~ZZ
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007219 - Notch signaling pathway
GO:0008270 - zinc ion binding
and 2 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1006
Hs

1 955
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Last updated: 15 Jul 2024