HitPredict

Interactor 1: MIB1 (Q86YT6)
E3 ubiquitin-protein ligase MIB1 (EC 2.3.2.27) (DAPK-interacting protein 1) (DIP-1) (Mind bomb homolog 1) (RING-type E3 ubiquitin transferase MIB1) (Zinc finger ZZ type with ankyrin repeat domain protein 2)
Gene: MIB1

Interactor 2: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	19690564
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1006 Hs			1 151
+	Hs
		1206094 MIB1_HUMAN (1-1006): 0: 867: 100.00		UB2D4_HUMAN (4-150): 7.3e-70: 208: 35.37
+	Hs
		849363 MIB1_HUMAN (1-1006): 0: 867: 100.00		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		919776 MIB1_HUMAN (1-1006): 0: 867: 100.00		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		895841 MIB1_HUMAN (1-1006): 0: 867: 100.00		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Hs
		849396 MIB2_HUMAN (14-1006): 0: 593: 29.05		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		919813 MIB2_HUMAN (14-1006): 0: 593: 29.05		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		829062 Q9H4D1_HUMAN (397-718): 4.03e-26: 117: 31.00		UBE2A_HUMAN (1-146): 7.59e-64: 193: 31.97