HitPredict

Interactor 1: RNF41 (Q8BH75)
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)
Gene: RNF41

Interactor 2: TBK1 (Q9WUN2)
Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (T2K) (TANK-binding kinase 1)
Gene: TBK1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.528

Property	Details
Experiments	19483718
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Mm			1 729
+	Hs
		585090 RO52_HUMAN (3-295): 1.95e-61: 204: 16.94		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		1019379 TRI26_HUMAN (3-301): 1.09e-51: 180: 12.62		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		1354523 TRI10_HUMAN (3-279): 5.06e-49: 171: 16.84		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Hs
		537119 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		TBK1_HUMAN (1-729): 0: 562: 94.10
+	Mm
		1143608 TRI27_MOUSE (3-275): 4.14e-47: 167: 15.11		TBK1_MOUSE (1-729): 0: 558: 100.00
+	Hs
		1050264 TRIM6_HUMAN (11-296): 9.77e-54: 184: 18.24		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		536827 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		1050263 TRIM7_HUMAN (13-277): 1.6e-43: 157: 14.78		IKKE_HUMAN (1-715): 7.37e-150: 455: 48.54
+	Hs
		158392 RO52_HUMAN (3-295): 1.95e-61: 204: 16.94		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Hs
		158386 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		IKKB_HUMAN (9-709): 4.06e-128: 400: 18.63
+	Hs
		584875 RO52_HUMAN (3-295): 1.95e-61: 204: 16.94		CDK2_HUMAN (6-312): 9.48e-120: 362: 20.97
+	Hs
		1296785 RNF41_HUMAN (1-317): 4.87e-90: 273: 99.69		MARK4_HUMAN (9-311): 1.6e-86: 290: 25.16
+	Hs
		167580 TRI22_HUMAN (3-300): 1.61e-53: 184: 17.21		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		167459 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		IKKA_HUMAN (9-643): 5.48e-119: 375: 20.53
+	Hs
		1290895 TRI11_HUMAN (3-295): 1.14e-56: 191: 13.92		MARK1_HUMAN (9-407): 3.57e-86: 290: 24.57
+	Hs
		262235 RO52_HUMAN (3-295): 1.95e-61: 204: 16.94		ULK1_HUMAN (13-222): 3.4e-26: 117: 34.10
+	Hs
		883160 TRI68_HUMAN (3-295): 3.8e-58: 196: 15.41		HUNK_HUMAN (15-224): 2.85e-21: 100: 33.95
+	Hs
		262230 TRI27_HUMAN (3-275): 1.78e-47: 168: 14.75		ULK1_HUMAN (13-222): 3.4e-26: 117: 34.10
+	Mm
		250797 TRI27_MOUSE (3-275): 4.14e-47: 167: 15.11		ULK1_MOUSE (13-222): 6.31e-26: 116: 33.64
+	Hs
		1318781 TRI39_HUMAN (9-271): 2.23e-49: 173: 16.54		DCLK3_HUMAN (14-238): 8.02e-23: 105: 30.22