HitPredict

Interactor 1: ELMO2 (Q8BHL5)
Engulfment and cell motility protein 2 (Protein ced-12 homolog A)
Gene: ELMO2

Interactor 2: DOCK1 (Q8BUR4)
Dedicator of cytokinesis protein 1 (180 kDa protein downstream of CRK) (DOCK180)
Gene: DOCK1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15102471
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DOCK_N~PH_12
Common GO terms	GO:0005829 - cytosol GO:0006909 - phagocytosis GO:0006915 - apoptotic process GO:0017124 - SH3 domain binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 732 Mm			1 1865
+	Hs
		1050489 ELMO2_HUMAN (1-732): 0: 1045: 97.13		DOCK1_HUMAN (1-1823): 0: 2255: 96.65
+	Mm
		1207128 ELMO1_MOUSE (1-730): 0: 1004: 73.98		DOCK1_MOUSE (1-1819): 0: 2266: 100.00
+	Hs
		1050484 ELMO1_HUMAN (1-730): 0: 1004: 74.12		DOCK1_HUMAN (1-1823): 0: 2255: 96.65
+	Mm
		1207312 ELMO3_MOUSE (1-731): 0: 933: 50.27		DOCK1_MOUSE (1-1819): 0: 2266: 100.00
+	Hs
		1050487 ELMO3_HUMAN (1-730): 0: 934: 49.52		DOCK1_HUMAN (1-1823): 0: 2255: 96.65
+	Hs
		1267934 ELMO2_HUMAN (1-732): 0: 1045: 97.13		DOCK2_HUMAN (1-1804): 0: 2037: 59.45
+	Hs
		1267020 ELMO1_HUMAN (1-730): 0: 1004: 74.12		DOCK2_HUMAN (1-1804): 0: 2037: 59.45
+	Hs
		1295265 ELMO2_HUMAN (1-732): 0: 1045: 97.13		DOCK5_HUMAN (1-1830): 0: 1993: 63.02
+	Mm
		1207130 ELMO1_MOUSE (1-730): 0: 1004: 73.98		DOCK2_MOUSE (1-1804): 0: 1994: 59.10
+	Hs
		1267024 ELMO1_HUMAN (1-730): 0: 1004: 74.12		DOCK5_HUMAN (1-1830): 0: 1993: 63.02
+	Hs
		1285559 ELMO3_HUMAN (1-730): 0: 934: 49.52		DOCK5_HUMAN (1-1830): 0: 1993: 63.02
+	Hs
		1224227 ELMO2_HUMAN (1-732): 0: 1045: 97.13		DOCK3_HUMAN (4-1860): 0: 1839: 36.47
+	Hs
		1230992 ELMO2_HUMAN (1-732): 0: 1045: 97.13		DOCK4_HUMAN (4-1862): 0: 1825: 36.34
+	Hs
		1224220 ELMO1_HUMAN (1-730): 0: 1004: 74.12		DOCK3_HUMAN (4-1860): 0: 1839: 36.47
+	Hs
		1061751 ELMO2_HUMAN (1-732): 0: 1045: 97.13		Q149N5_HUMAN (4-1862): 0: 1795: 35.41
+	Hs
		1230987 ELMO1_HUMAN (1-730): 0: 1004: 74.12		DOCK4_HUMAN (4-1862): 0: 1825: 36.34
+	Hs
		1224225 ELMO3_HUMAN (1-730): 0: 934: 49.52		DOCK3_HUMAN (4-1860): 0: 1839: 36.47
+	Hs
		1230990 ELMO3_HUMAN (1-730): 0: 934: 49.52		DOCK4_HUMAN (4-1862): 0: 1825: 36.34
+	Dm
		1362934 Q9VKB2_DROME (5-730): 0: 827: 44.01		Q9VCH4_DROME (1-1822): 0: 1842: 38.72
+	Dm
		81396 Q9VKB2_DROME (5-730): 0: 827: 44.01		B7Z0R2_DROME (4-1764): 0: 1684: 36.01